Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 6/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.37 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.37 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.37 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.37 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.37 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.37 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.37 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19209443 | 0.90 | S1PR1 (0.51) | XDHS1PR1HSD17B10 | |
| SCHEMBL19257720 | 0.87 | XDH (0.42) | XDHS1PR1NPC1RAB9AHSD17B10 | |
| SCHEMBL19209491 | 0.79 | S1PR1 (0.46) | XDHS1PR1NPC1RAB9AHSD17B10 | |
| SCHEMBL19209475 | 0.78 | XDH (0.41) | XDHS1PR1NPC1RAB9AHSD17B10 | |
| SCHEMBL15602073 | 0.78 | RAB9A (0.44) | NPC1RAB9AHSD17B10TP53MTNR1A | |
| SCHEMBL1891972 | 0.78 | POLB (0.50) | S1PR1HSD17B10MTNR1AMTNR1B | |
| SCHEMBL38659657 | 0.78 | POLB (0.50) | S1PR1HSD17B10MTNR1AMTNR1B | |
| SCHEMBL19257588 | 0.78 | HSD17B10 (0.43) | NPC1RAB9AHSD17B10MTNR1AMTNR1B | |
| SCHEMBL19209414 | 0.76 | FFAR1 (0.50) | XDHS1PR1MTNR1AMTNR1B | |
| SCHEMBL38659061 | 0.75 | MTNR1A (0.42) | HSD17B10MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017134146-A1 | GPBP INHIBITORS AND USES AND SCALEABLE SYNTHESIS THEREOF | FIBROSTATIN, S.L. (ES) | 2017-08-10 | — | — | WO | disclosed |