SCHEMBL19258029

SCHEMBL19258029

Cc1cc(C)c(C)c(-c2ncnc3cc(CCC(F)(F)F)ccc23)c1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
IRAK4 Q9NWZ3 1/20 0.33
PRKDC P78527 1/20 0.32
EGFR P00533 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19258220 0.85 PRKDC (0.33) IRAK4PRKDCEGFR
SCHEMBL19258028 0.83 SIGMAR1 (0.37) IRAK4PRKDC
SCHEMBL19258273 0.83 PRKDC (0.32) PRKDC
SCHEMBL19257828 0.81 ROCK1 (0.34)
SCHEMBL19258222 0.81 SIGMAR1 (0.42) PRKDC
SCHEMBL17666808 0.80 SIK2 (0.37) IRAK4PRKDCEGFR
SCHEMBL26060495 0.80
SCHEMBL25776449 0.73 ADORA2A (0.49) EGFR
SCHEMBL19143215 0.73 LMNA (0.36) IRAK4PRKDCEGFR
SCHEMBL26060382 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3205658-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2017-08-16 EP disclosed