Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19250590 | 0.78 | GRIN1 (0.34) | GRIN2B | |
| SCHEMBL19258476 | 0.78 | GRIN1 (0.33) | GRIN2B | |
| SCHEMBL19258560 | 0.74 | GRIN1 (0.34) | GRIN2B | |
| SCHEMBL19258556 | 0.73 | MAP3K14 (0.30) | — | |
| SCHEMBL19258499 | 0.69 | PDE10A (0.34) | — | |
| SCHEMBL15290567 | 0.62 | ALDH1A1 (0.49) | MEN1TSHRKMT2AMAPT | |
| SCHEMBL3545678 | 0.62 | MAPT (0.42) | MEN1TSHRKMT2AMAPT | |
| SCHEMBL9193384 | 0.61 | CYP2D6 (0.45) | — | |
| SCHEMBL9195181 | 0.61 | HTT (0.46) | MEN1KMT2AMAPT | |
| SCHEMBL19258987 | 0.60 | GRIN1 (0.35) | GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133657-A1 | PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA | SAVIRA PHARMACEUTICALS GMBH (AT) | 2017-08-10 | — | — | WO | disclosed |