Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 3/20 | 0.40 |
| ▸ | YTHDF2 | Q9Y5A9 | 2/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 6/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19801401 | 0.78 | GRM4 (0.33) | GRM4MAPK1 | |
| SCHEMBL6358084 | 0.77 | MAPK1 (0.38) | YTHDC1YTHDF2GRM4MAPK1 | |
| SCHEMBL3950985 | 0.73 | PDPK1 (0.38) | YTHDC1YTHDF2GRM4MAPK1PDPK1 | |
| SCHEMBL14776080 | 0.72 | CCNB2 (0.49) | — | |
| SCHEMBL19801454 | 0.72 | GRM4 (0.63) | GRM4 | |
| SCHEMBL12038443 | 0.69 | GPR84 (0.42) | GRM4PDPK1 | |
| SCHEMBL30773519 | 0.69 | GPR84 (0.42) | GRM4PDPK1 | |
| SCHEMBL14906014 | 0.69 | GRM4 (0.64) | GRM4 | |
| SCHEMBL30876173 | 0.68 | MAPK1 (0.35) | MAPK1 | |
| SCHEMBL14763598 | 0.68 | DYRK1A (0.38) | MAPK1PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133657-A1 | PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA | SAVIRA PHARMACEUTICALS GMBH (AT) | 2017-08-10 | — | — | WO | disclosed |