Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.34 |
| ▸ | CDK1 | P06493 | 3/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.34 |
| ▸ | GSK3A | P49840 | 3/20 | 0.34 |
| ▸ | GSK3B | P49841 | 3/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.34 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6358084 | 0.75 | MAPK1 (0.38) | MAPK1 | |
| SCHEMBL30180924 | 0.71 | DYRK1A (0.38) | MAPK1CCNB2CDK1CCNB1GSK3A | |
| SCHEMBL30316980 | 0.71 | MAPK1 (0.35) | MAPK1 | |
| SCHEMBL3950985 | 0.71 | PDPK1 (0.38) | MAPK1CCNB2CDK1CCNB1GSK3A | |
| SCHEMBL14906033 | 0.71 | MAPK1 (0.45) | MAPK1 | |
| SCHEMBL14763598 | 0.71 | DYRK1A (0.38) | MAPK1CCNB2CDK1CCNB1GSK3A | |
| SCHEMBL24283772 | 0.69 | KDM4E (0.33) | CCNB2CDK1CCNB1CDK5CDK5R1 | |
| SCHEMBL19641301 | 0.69 | GRM4 (0.31) | — | |
| SCHEMBL29490926 | 0.69 | GRM4 (0.31) | — | |
| SCHEMBL28570318 | 0.69 | ADORA3 (0.38) | MAPK1CCNB2CDK1CCNB1GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12545684-B2 | CDK2 inhibitors | BLUEPRINT MEDICINES CORPORATION (US) | 2026-02-10 | — | — | US | disclosed |
| US-20240383902-A1 | CDK2 INHIBITORS | BLUEPRINT MEDICINES CORPORATION | 2024-11-21 | — | — | US | disclosed |
| US-11970498-B2 | CDK2 inhibitors | BLUEPRINT MEDICINES CORPORATION (US) | 2024-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11970498-B2 | CDK2 inhibitors | CDK2, CDK20, CDK2AP1 | MAPK1 200/4885CCNB2 31/4885CDK1 6/4885 |
| US-20240383902-A1 | CDK2 INHIBITORS | CDK2, CDK20, CDK2AP1 | MAPK1 200/4885CCNB2 31/4885CDK1 6/4885 |
| US-12545684-B2 | CDK2 inhibitors | CDK2, CDK4, CDK1 | MAPK1 368/4885CCNB2 44/4885CDK1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.