Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5983555 | 0.71 | MMP8 (0.57) | PIN1MEN1KMT2ANPC1MMP8 | |
| SCHEMBL10756249 | 0.71 | MMP8 (0.57) | PIN1MEN1KMT2ANPC1MMP8 | |
| Toluene SCHEMBL7044583 | 0.71 | PIN1 (0.53) | PIN1MEN1KMT2ANPC1MMP8 | |
| SCHEMBL304815 | 0.71 | MMP8 (0.57) | PIN1MEN1KMT2ANPC1MMP8 | |
| SCHEMBL5837138 | 0.70 | MEN1 (0.46) | PIN1MEN1KMT2ANPC1TSHR | |
| SCHEMBL324209 | 0.69 | MMP8 (0.56) | PIN1MEN1KMT2ANPC1MMP8 | |
| Toluene SCHEMBL8038714 | 0.69 | PIN1 (0.51) | PIN1MEN1KMT2ANPC1MMP8 | |
| Phenol SCHEMBL5006868 | 0.69 | PIN1 (0.51) | PIN1MEN1KMT2ANPC1MMP8 | |
| SCHEMBL4290959 | 0.69 | MMP8 (0.56) | PIN1MEN1KMT2ANPC1MMP8 | |
| SCHEMBL2400228 | 0.69 | MMP8 (0.56) | PIN1MEN1KMT2ANPC1MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017136466-A1 | HEME PROTEIN CATALYSTS FOR CARBON-SILICON BOND FORMATION IN VITRO AND IN VIVO | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2017-08-10 | — | — | WO | disclosed |