Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 2/20 | 0.53 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.43 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.43 |
| ▸ | ITGAL | P20701 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18075525 | 0.96 | ECE1 (0.56) | ECE1ITGB2ICAM1ITGALCA2 | |
| SCHEMBL15461 | 0.96 | ECE1 (0.56) | ECE1ITGB2ICAM1ITGALCA2 | |
| SCHEMBL150536 | 0.93 | ECE1 (0.53) | ECE1ITGB2ICAM1ITGALCA2 | |
| SCHEMBL7258586 | 0.93 | ECE1 (0.53) | ECE1ITGB2ICAM1ITGALCA2 | |
| SCHEMBL31182997 | 0.93 | ECE1 (0.53) | ECE1ITGB2ICAM1ITGALCA2 | |
| SCHEMBL6852847 | 0.93 | ECE1 (0.53) | ECE1ITGB2ICAM1ITGALCA2 | |
| SCHEMBL6136566 | 0.93 | ECE1 (0.53) | ECE1ITGB2ICAM1ITGALCA2 | |
| SCHEMBL7148009 | 0.93 | ECE1 (0.53) | ECE1ITGB2ICAM1ITGALCA2 | |
| SCHEMBL1246595 | 0.93 | ECE1 (0.53) | ECE1ITGB2ICAM1ITGALCA2 | |
| SCHEMBL9752652 | 0.93 | ECE1 (0.53) | ECE1ITGB2ICAM1ITGALCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3615502-A1 | THERAPEUTIC COMPOUNDS AND METHODS | University Of Tasmania (AU) | 2020-03-04 | — | — | EP | disclosed |
| EP-3416975-A1 | NOVEL ALPHA CONOTOXIN PEPTIDES | The University of Queensland (AU) | 2018-12-26 | — | — | EP | disclosed |
| WO-2018191789-A1 | THERAPEUTIC COMPOUNDS AND METHODS | UNIVERSITY OF TASMANIA (AU) | 2018-10-25 | — | — | WO | disclosed |
| WO-2017139845-A1 | NOVEL ALPHA CONOTOXIN PEPTIDES | THE UNIVERSITY OF QUEENSLAND (AU) | 2017-08-24 | — | — | WO | disclosed |