SCHEMBL150536

SCHEMBL150536

NC(=O)C[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)CC(N)=O)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ECE1 P42892 3/20 0.53
ITGB2 P05107 2/20 0.43
ICAM1 P05362 2/20 0.43
ITGAL P20701 2/20 0.43
PDCD1LG2 Q9BQ51 1/20 0.43
CD274 Q9NZQ7 1/20 0.43
CA2 P00918 4/20 0.41
CA1 P00915 3/20 0.41
ALDH1A1 P00352 1/20 0.41
RAB9A P51151 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
CTSD P07339 1/20 0.39
BACE1 P56817 1/20 0.39
GNPAT O15228 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4347089 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL1246595 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL9752652 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL757072 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL6852847 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL6136566 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL7148009 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL7258586 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL31182997 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL18075525 0.96 ECE1 (0.56) ECE1ITGB2ICAM1ITGALPDCD1LG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8198 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110551187-B Chemically synthesized H7N9 avian influenza virus NA protein extracellular region antigen segment, preparation method and application 新乡学院 2022-09-16 CN claimed
EP-3335728-A1 BIOCHEMICALLY STABILIZED HIV-1 ENV TRIMER VACCINE Children's Medical Center Corporation (US) 2018-06-20 EP claimed
EP-2340038-B1 BIOCHEMICALLY STABILIZED HIV-1 ENV TRIMER VACCINE CHILDREN'S MEDICAL CENTER CORP (US) 2018-01-10 EP claimed
CN-106478803-A Microhyla puichra (Hallowell) insulinotropic peptide and its gene and the application in pharmacy 南方医科大学 2017-03-08 CN claimed
US-20110244513-A1 ISOLATED MAMMALIAN MEMBRANE PROTEIN GENES; RELATED REAGENTS SCHERING CORP. 2011-10-06 US claimed
CN-101275146-B Production method for streptococcus specific bacteriophage lyase UNIV ZHEJIANG SHUREN 2010-08-04 CN claimed
CN-101333252-A Decorin gene capable of restraining tumour cell from growing and transferring, preparation method and application thereof WENZHOU MEDICAL COLLEGE (CN) 2008-12-31 CN claimed
EP-1980573-A2 Isolated dendritic cell membrane protein genes SCHERING CORPORATION (US) 2008-10-15 EP claimed
EP-1979001-A2 BINDING PROTEINS SPECIFIC FOR INSULIN-LIKE GROWTH FACTORS AND USES THEREOF AstraZeneca AB (SE) 2008-10-15 EP claimed
CN-100386343-C SARS virus S protein and N protein fusion protein, and preparation and use thereof YUEXI LI (CN) 2008-05-07 CN claimed
EP-0531315-A1 AN ENZYME CAPABLE OF DEGRADING CELLULOSE OR HEMICELLULOSE. NOVO NORDISK AS (DK) 1993-03-17 EP claimed
EP-0506868-A1 IMMUNOLOGICALLY ACTIVE PROTEINES FROM BORRELIA BURGDORFERI, RELATED TEST KITS AND VACCINE. MIKROGEN MOLEKULARBIOL ENTW (DE) 1992-10-07 EP claimed
CN-1064704-A The DNA of curculigineB, coding curculigineB and the method for producing curculigineB KURIHARA YOSHIE (JP) 1992-09-23 CN claimed
EP-0502146-A1 MAREK'S DISEASE HERPESVIRUS DNA SEGMENT ENCODING GLYCOPROTEIN gE MICHIGAN STATE UNIVERSITY (US) 1992-09-09 EP claimed
US-5110905-A Insecticide against tobacco budworm larvae REPLIGEN CORPORATION (US) 1992-05-05 US claimed
WO-1992003547-A1 MAREK'S DISEASE HERPESVIRUS DNA SEGMENT ENCODING GLYCOPROTEINS, gD, gI AND gE MICHIGAN STATE UNIVERSITY (US) 1992-03-05 WO claimed
WO-1991017244-A1 AN ENZYME CAPABLE OF DEGRADING CELLULOSE OR HEMICELLULOSE NOVO NORDISK A/S (DK) 1991-11-14 WO claimed
WO-1991009870-A1 IMMUNOLOGICALLY ACTIVE PROTEINES FROM BORRELIA BURGDORFERI, RELATED TEST KITS AND VACCINE MIKROGEN MOLEKULARBIOLOGISCHE ENTWICKLUNGS-GMBH (DE) 1991-07-11 WO claimed
WO-1991008310-A1 DETECTION OF HUMAN ADENOVIRUS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1991-06-13 WO claimed
EP-0292435-A1 Zea mays plants and transgenic zea mays plants regenerated from protoplasts or protoplast-derived cells CIBA-GEIGY AG (CH) 1988-11-23 EP claimed