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Sugi Predict / Compounds / SCHEMBL1246595

SCHEMBL1246595

SCHEMBL1246595

NC(=O)C[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)CC(N)=O)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ ECE1 P42892 3/20 0.53
▸ ITGB2 P05107 2/20 0.43
▸ ICAM1 P05362 2/20 0.43
▸ ITGAL P20701 2/20 0.43
▸ PDCD1LG2 Q9BQ51 1/20 0.43
▸ CD274 Q9NZQ7 1/20 0.43
▸ CA2 P00918 4/20 0.41
▸ CA1 P00915 3/20 0.41
▸ ALDH1A1 P00352 1/20 0.41
▸ RAB9A P51151 1/20 0.41
▸ MEN1 O00255 1/20 0.40
▸ KMT2A Q03164 1/20 0.40
▸ CTSD P07339 1/20 0.39
▸ BACE1 P56817 1/20 0.39
▸ GNPAT O15228 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4347089 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL9752652 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL757072 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL6852847 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL6136566 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL7148009 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL7258586 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL150536 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL31182997 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL18075525 0.96 ECE1 (0.56) ECE1ITGB2ICAM1ITGALPDCD1LG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2286221-A2 METHODS FOR ASSAYING COMPOUNDS OR AGENTS FOR ABILITY TO DISPLACE POTENT LIGANDS OF HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE Cayman Chemical Company (US) 2011-02-23 — — EP claimed
US-20090286261-A1 METHOD FOR ASSAYING COMPOUNDS OR AGENTS FOR ABILITY TO DISPLACE POTENT LIGANDS OF HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE CAYMAN CHEMICAL COMPANY (US) 2009-11-19 — — US claimed
WO-2009140364-A2 METHODS FOR ASSAYING COMPOUNDS OR AGENTS FOR ABILITY TO DISPLACE POTENT LIGANDS OF HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE CAYMAN CHEMICAL COMPANY (US) 2009-11-19 — — WO claimed
CN-1335889-A Chimeric genes encoding antigenic determinants of four proteins of l.infantum LETI LAB (ES) 2002-02-13 — — CN claimed
EP-1141305-A1 CHIMERIC GENE ENCODING THE ANTIGENIC DETERMINANTS OF FOUR PROTEINS OF L. INFANTUM C.B.F. Leti S.A. (ES) 2001-10-10 — — EP claimed
WO-2000039298-A1 CHIMERIC GENE ENCODING THE ANTIGENIC DETERMINANTS OF FOUR PROTEINS OF L. INFANTUM C.B.F. LETI S.A. (ES) 2000-07-06 — — WO claimed
CN-113412329-B Phloroglucinol resistant cells, particularly yeasts 米其林集团总公司 2024-03-01 — — CN disclosed
CN-114057861-B bio-PROTAC artificial protein targeting UBE2C 深圳湾实验室坪山生物医药研发转化中心 2023-11-21 — — CN disclosed
CN-116964220-A Multiplex analysis of RNA and DNA modifications 阿丽达生物科学公司 2023-10-27 — — CN disclosed
CN-116926170-A Nucleic acid detection method based on sulfur modified nucleic acid and sulfur modified nucleic acid recognition protein 上海交通大学 2023-10-24 — — CN disclosed
CN-111978407-B Heterologous expression method of lysine decarboxylase from thermophilic bacteria and application thereof 上海凯赛生物技术股份有限公司 2023-10-13 — — CN disclosed
CN-113767170-B His-MBP-labeled DNA endonucleases for facilitating enzymatic removal 武汉爱博泰克生物科技有限公司 2023-10-03 — — CN disclosed
CN-111566120-B 3' cyclic dinucleotides with phosphonate bonds of activated STING adaptor protein 捷克共和国有机化学与生物化学研究所 2023-09-29 — — CN disclosed
WO-2000039298-A1 CHIMERIC GENE ENCODING THE ANTIGENIC DETERMINANTS OF FOUR PROTEINS OF L. INFANTUM C.B.F. LETI S.A. (ES) 2000-07-06 — — WO disclosed
EP-0991665-A1 PEPTIDES AND COMPOUNDS THAT BIND TO THE IL-5 RECEPTOR GLAXO GROUP LIMITED (GB) 2000-04-12 — — EP disclosed
EP-0991659-A1 PEPTIDES AND COMPOUNDS THAT BIND TO THE IL-5 RECEPTOR GLAXO GROUP LIMITED (GB) 2000-04-12 — — EP disclosed
WO-1998057980-A1 PEPTIDES AND COMPOUNDS THAT BIND TO THE IL-5 RECEPTOR GLAXO GROUP LIMITED (GB) 1998-12-23 — — WO disclosed
WO-1998057991-A1 PEPTIDES AND COMPOUNDS THAT BIND TO THE IL-5 RECEPTOR GLAXO GROUP LIMITED (GB) 1998-12-23 — — WO disclosed
CN-1150821-A Process for producing trans-4-hydroxy-L-proline KYOWA HAKKO KOGYO KK (JP) 1997-05-28 — — CN disclosed
WO-1996024605-A1 METHODS AND COMPOSITIONS FOR ALTERING SEXUAL BEHAVIOR THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 1996-08-15 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090286261-A1 METHOD FOR ASSAYING COMPOUNDS OR AGENTS FOR ABILITY TO DISPLACE POTENT LIGANDS OF HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE HPGDS, HPGD, GMDS ECE1 417/4885ITGB2 4486/4885ICAM1 1629/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.