Sugi Predict

Sugi Predict / Compounds / SCHEMBL7258586

SCHEMBL7258586

SCHEMBL7258586

NC(=O)C[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)CC(N)=O)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ ECE1 P42892 3/20 0.53
▸ ITGB2 P05107 2/20 0.43
▸ ICAM1 P05362 2/20 0.43
▸ ITGAL P20701 2/20 0.43
▸ PDCD1LG2 Q9BQ51 1/20 0.43
▸ CD274 Q9NZQ7 1/20 0.43
▸ CA2 P00918 4/20 0.41
▸ CA1 P00915 3/20 0.41
▸ ALDH1A1 P00352 1/20 0.41
▸ RAB9A P51151 1/20 0.41
▸ MEN1 O00255 1/20 0.40
▸ KMT2A Q03164 1/20 0.40
▸ CTSD P07339 1/20 0.39
▸ BACE1 P56817 1/20 0.39
▸ GNPAT O15228 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4347089 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL1246595 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL9752652 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL757072 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL6852847 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL6136566 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL7148009 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL150536 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL31182997 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL18075525 0.96 ECE1 (0.56) ECE1ITGB2ICAM1ITGALPDCD1LG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114107252-B CL7 protein, high-activity recombinant TET enzyme CL7-NgTET1, prokaryotic expression vector and application 翌圣生物科技(上海)股份有限公司 2023-12-29 — — CN disclosed
CN-113621037-B Cucumber CsHEC2 protein and application of encoding gene thereof in reducing fruit thorn tumor density 中国农业大学 2023-11-03 — — CN disclosed
CN-116745410-A Genetically engineered bacteria capable of producing cytokinins with isoprenoid side chains 阿西耶斯生物公司 2023-09-12 — — CN disclosed
US-20230256051-A1 MODIFIED KISSPEPTIN RECEPTOR AGONISTS FOR FATTY LIVER DISEASE UNIV RUTGERS (US) 2023-08-17 — — US disclosed
CN-116323952-A LYSM receptor motif 奥尔胡斯大学 2023-06-23 — — CN disclosed
CN-109312315-B Carrier-free delivery of gene-editing proteins and compositions to cells and tissues 阿维塔斯有限公司 2023-06-09 — — CN disclosed
CN-115427575-A Fusion protein of Z-domain and cryptocalcitonin having improved reactivity, stability and antibody recovery rate and method for separating and purifying antibody using the same 韩国窑业技术院 2022-12-02 — — CN disclosed
CN-115335392-A Suppression of plant shade-avoidance response 成对植物服务股份有限公司 2022-11-11 — — CN disclosed
CN-112979781-B Sebastes schlegeli IL-1 beta recombinant protein and preparation method and application thereof 中国海洋大学 2022-05-17 — — CN disclosed
CN-114107252-A CL7 protein, high-activity recombinant TET enzyme CL7-NgTET1, prokaryotic expression vector and application thereof 翌圣生物科技(上海)股份有限公司 2022-03-01 — — CN disclosed
CN-101198690-A Agent containing VDUP1 protein or its encoding gene for differentiating hemopoietic stem cell into natural killer cell, and method for differentiating hemopoietic stem cell into natural killer cell by KOREA RES INST OF BIOSCIENCE (KR) 2008-06-11 — — CN disclosed
US-6641815-B2 Diagnosis of malaria; protein; genetic engineering THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY 2003-11-04 — — US disclosed
EP-0781326-A4 THE IRS FAMILY OF GENES JOSLIN DIABETES CENTER INC (US) 1999-10-06 — — EP disclosed
EP-0781326-A1 THE IRS FAMILY OF GENES THE JOSLIN DIABETES CENTER, INC. (US) 1997-07-02 — — EP disclosed
WO-1996024605-A1 METHODS AND COMPOSITIONS FOR ALTERING SEXUAL BEHAVIOR THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 1996-08-15 — — WO disclosed
WO-1996010629-A1 THE IRS FAMILY OF GENES JOSLIN DIABETES CENTER, INC. (US) 1996-04-11 — — WO disclosed
EP-0679185-A1 RAS ASSOCIATED GAP PROTEINS SCHERING CORPORATION (US) 1995-11-02 — — EP disclosed
WO-1994016069-A2 RAS ASSOCIATED GAP PROTEINS SCHERING CORPORATION (US) 1994-07-21 — — WO disclosed
WO-1993020219-A1 CONTROL AND/OR PREVENTION OF BINDING OF NF-KB/REL/DORSAL (NRD) FAMILY PROTEINS TO DNA THE GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1993-10-14 — — WO disclosed
WO-1991008756-A1 NOVEL MALARIAL SPOROZOITE PEPTIDE ANTIGENS BIOMEDICAL RESEARCH INSTITUTE (US) 1991-06-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230256051-A1 MODIFIED KISSPEPTIN RECEPTOR AGONISTS FOR FATTY LIVER DISEASE KISS1R, GLP1R, GPR119 ECE1 1002/4885ITGB2 4471/4885ICAM1 2110/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.