SCHEMBL6852847

SCHEMBL6852847

NC(=O)C[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)CC(N)=O)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ECE1 P42892 3/20 0.53
ITGB2 P05107 2/20 0.43
ICAM1 P05362 2/20 0.43
ITGAL P20701 2/20 0.43
PDCD1LG2 Q9BQ51 1/20 0.43
CD274 Q9NZQ7 1/20 0.43
CA2 P00918 4/20 0.41
CA1 P00915 3/20 0.41
ALDH1A1 P00352 1/20 0.41
RAB9A P51151 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
CTSD P07339 1/20 0.39
BACE1 P56817 1/20 0.39
GNPAT O15228 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4347089 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL1246595 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL9752652 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL757072 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL6136566 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL7148009 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL7258586 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL150536 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL31182997 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL18075525 0.96 ECE1 (0.56) ECE1ITGB2ICAM1ITGALPDCD1LG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117858945-A Modification of HECT E3 ubiquitin ligase gene for improved yield traits 成对植物服务股份有限公司 2024-04-09 CN disclosed
CN-110582567-B Genetically modified trehalase-expressing yeasts and fermentation methods using such genetically modified yeasts 嘉吉公司 2024-03-08 CN disclosed
CN-114057861-B bio-PROTAC artificial protein targeting UBE2C 深圳湾实验室坪山生物医药研发转化中心 2023-11-21 CN disclosed
CN-116547263-A Methods and cells for producing substituted cannabinoids and precursors using modified enzymes 海牙森生物公司 2023-08-04 CN disclosed
CN-114716525-B Xanthoceras sorbifolia bunge dry heat induction transcription factor XsWRKY33 and application thereof 大连民族大学 2023-05-26 CN disclosed
CN-113999292-B Polypeptide inhibitors targeting respiratory viruses 中国农业大学 2023-05-26 CN disclosed
CN-113061590-B Algae toxin degrading enzyme, composite material and application 华中师范大学 2023-02-17 CN disclosed
US-20230044668-A1 UNIVERSAL ORAL DELIVERY DEVICE OF INTACT THERAPEUTIC POLYPEPTIDES WITH HIGH BIOAVAILABILITY PANARUM CORP (US) 2023-02-09 US disclosed
CN-112375767-B Artemisia apiacea WRKY transcription factor AaWRKY4 gene and application thereof 衡阳师范学院 2022-12-02 CN disclosed
CN-115335392-A Suppression of plant shade-avoidance response 成对植物服务股份有限公司 2022-11-11 CN disclosed
CN-1329504-A F1t4 (VEGFR-3) as target for tumor imaging and anti-tumor therapy LUDWIG INST CANCER RES (US) 2002-01-02 CN disclosed
EP-0948508-A4 NOVEL CODING SEQUENCES FROM HERPES SIMPLEX VIRUS TYPE-2 SMITHKLINE BEECHAM CORP (US) 2001-11-07 EP disclosed
US-6114158-A RECOMBINANT DNA HAVING DEFINED NUCLEOTIDE SEQUENCE; FOR PRODUCTION OF CELLULASE ENZYME FOR USE IN PAPER/TEXTILE INDUSTRIES AND IN PRODUCTION OF ETHANOL UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2000-09-05 US disclosed
US-6096865-A FLUORESCENT POLYPEPTIDES; FOR SIMPLE AND EFFICIENT MONITORING OF THE EXPRESSION OF A PARTICULAR PROTEIN IN CELLS AMGEN INC. (US) 2000-08-01 US disclosed
US-6080400-A BACTERIAL HOST CELL EXPRESSES A VECTOR ENCODING A POLYHISTIDINE AFFINITY TAG AND A PROTEIN COMPRISING AT LEAST A PORTION OF E. COLI TYPE 2 VEROTOXIN, EXPRESSED AS A SOLUBLE PROTEIN OPHIDIAN PHARMACEUTICALS, INC. 2000-06-27 US disclosed
US-6018020-A VIRICIDES WHICH ARE PROTEASE INHIBITORS AGAINST HEPATITIS C AND HEPATITIS G HOFFMAN-LA ROCHE INC. (US) 2000-01-25 US disclosed
EP-0948508-A1 NOVEL CODING SEQUENCES FROM HERPES SIMPLEX VIRUS TYPE-2 SMITHKLINE BEECHAM CORPORATION (US) 1999-10-13 EP disclosed
WO-1998020016-A1 NOVEL CODING SEQUENCES FROM HERPES SIMPLEX VIRUS TYPE-2 SMITHKLINE BEECHAM CORPORATION (US) 1998-05-14 WO disclosed
WO-1998018927-A1 CANDIDA ALBICANS PROTEINS ASSOCIATED WITH VIRULENCE AND HYPHAL FORMATION AND USES THEREOF NATIONAL RESEARCH COUNCIL OF CANADA (CA) 1998-05-07 WO disclosed
WO-1991008756-A1 NOVEL MALARIAL SPOROZOITE PEPTIDE ANTIGENS BIOMEDICAL RESEARCH INSTITUTE (US) 1991-06-27 WO disclosed