Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31055695 | 0.96 | NLRP3 (0.48) | NLRP3GAAPDK1PDK2PDK3 | |
| SCHEMBL26975350 | 0.85 | NLRP3 (0.44) | NLRP3GAA | |
| SCHEMBL31055720 | 0.84 | GAA (0.39) | NLRP3GAASCN9A | |
| SCHEMBL22460320 | 0.84 | GAA (0.52) | NLRP3GAA | |
| SCHEMBL31055693 | 0.82 | NLRP3 (0.48) | NLRP3GAA | |
| SCHEMBL26975351 | 0.82 | NLRP3 (0.52) | NLRP3 | |
| SCHEMBL31055701 | 0.81 | NLRP3 (0.47) | NLRP3GAA | |
| SCHEMBL31055732 | 0.81 | NLRP3 (0.47) | NLRP3GAA | |
| SCHEMBL31055707 | 0.81 | NLRP3 (0.47) | NLRP3GAA | |
| SCHEMBL31055689 | 0.78 | NLRP3 (0.47) | NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3416948-A1 | SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME | The University Of Queensland (AU) | 2018-12-26 | — | — | EP | disclosed |
| WO-2017140778-A1 | SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME | THE UNIVERSITY OF QUEENSLAND (AU) | 2017-08-24 | — | — | WO | disclosed |