Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 13/20 | 0.69 |
| ▸ | ATM | Q13315 | 10/20 | 0.49 |
| ▸ | PRKDC | P78527 | 1/20 | 0.49 |
| ▸ | ATR | Q13535 | 1/20 | 0.49 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19259482 | 0.82 | PIK3C3 (1.00) | PIK3C3ATM | |
| SCHEMBL19259436 | 0.76 | PIK3C3 (1.00) | PIK3C3 | |
| SCHEMBL19259552 | 0.76 | PIK3C3 (1.00) | PIK3C3 | |
| SCHEMBL14983939 | 0.71 | PRKDC (0.46) | PIK3C3ATMPRKDCATR | |
| SCHEMBL31463645 | 0.71 | ATM (0.45) | PIK3C3ATMPRKDCATR | |
| SCHEMBL26633119 | 0.70 | NOTUM (0.50) | — | |
| SCHEMBL30403552 | 0.70 | NOTUM (0.50) | — | |
| SCHEMBL24681252 | 0.69 | LMNA (0.52) | PIK3C3ATMPRKDCATR | |
| SCHEMBL4855532 | 0.69 | LMNA (0.52) | PIK3C3ATMPRKDCATR | |
| SCHEMBL24680783 | 0.69 | LMNA (0.52) | PIK3C3ATMPRKDCATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3416945-A1 | 6-ARYL-4-MORPHOLIN-1-YLPYRIDONE COMPOUNDS USEFUL FOR THE TREATMENT OF CANCER AND DIABETES | Sprint Bioscience AB (SE) | 2018-12-26 | — | — | EP | disclosed |
| WO-2017140841-A1 | 6-ARYL-4-MORPHOLIN-1-YLPYRIDONE COMPOUNDS USEFUL FOR THE TREATMENT OF CANCER AND DIABETES | SPRINT BIOSCIENCE AB (SE) | 2017-08-24 | — | — | WO | disclosed |