Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.39 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.39 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.39 |
| ▸ | CRACR2A | Q9BSW2 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2733507 | 0.81 | IL2 (0.51) | LMNAMEN1KMT2ATRPC3ORAI1 | |
| SCHEMBL1827870 | 0.81 | POLB (0.53) | LMNATRPC3ORAI1TRPC5CRACR2A | |
| SCHEMBL8299313 | 0.80 | LMNA (0.49) | LMNAMEN1KMT2ATRPC3ORAI1 | |
| SCHEMBL19519193 | 0.70 | STIM1 (0.44) | MEN1KMT2AORAI1ALDH1A1NPC1 | |
| SCHEMBL1827209 | 0.70 | ORAI1 (0.56) | LMNAMEN1KMT2ATRPC3ORAI1 | |
| SCHEMBL17644785 | 0.69 | IL2 (0.46) | ORAI1NPC1RAB9A | |
| SCHEMBL19262118 | 0.69 | IL2 (0.64) | MEN1KMT2AORAI1 | |
| SCHEMBL1828387 | 0.68 | LMNA (0.52) | LMNATRPC3ORAI1TRPC5CRACR2A | |
| SCHEMBL16363177 | 0.68 | LMNA (0.52) | LMNAMEN1KMT2ATRPC3ORAI1 | |
| SCHEMBL8263207 | 0.67 | IMPDH2 (0.48) | LMNAORAI1ALDH1A1NPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9737534-B2 | Oxazoline and isoxazoline derivatives as CRAC modulators | LUPIN LIMITED (IN) | 2017-08-22 | — | — | US | disclosed |