Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 14/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2597419 | 0.86 | SLC6A3 (0.40) | SLC6A3SLC6A2ACHESLC6A4 | |
| SCHEMBL12777592 | 0.79 | NLRP3 (0.41) | NLRP3 | |
| SCHEMBL31384688 | 0.76 | SLC6A3 (0.45) | SLC6A3SLC6A2ACHESLC6A4 | |
| SCHEMBL11276545 | 0.76 | PTGS2 (0.43) | NLRP3 | |
| SCHEMBL8128143 | 0.75 | CA12 (0.39) | SLC6A3SLC6A2ACHESLC6A4 | |
| SCHEMBL8636289 | 0.74 | SLC6A3 (0.53) | SLC6A3SLC6A2ACHESLC6A4 | |
| SCHEMBL18803284 | 0.73 | NLRP3 (0.35) | NLRP3 | |
| SCHEMBL8648768 | 0.73 | CA1 (0.52) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL5656613 | 0.73 | SLC6A3 (0.45) | SLC6A3SLC6A2ACHESLC6A4 | |
| SCHEMBL29013549 | 0.73 | SLC6A3 (0.42) | SLC6A3SLC6A2ACHESLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571857-B1 | PROCESS FOR THE PREPARATION OF PYRIMIDINONE COMPOUNDS | GLAXO GROUP LTD (GB) | 2017-08-23 | — | — | EP | disclosed |