Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.43 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4171406 | 0.87 | MAPT (0.38) | KMT2AALDH1A1HTTGAAHPGD | |
| SCHEMBL7132351 | 0.84 | L3MBTL1 (0.46) | KMT2AALDH1A1HTTGAAHPGD | |
| SCHEMBL4152423 | 0.80 | KMT2A (0.46) | KMT2AALDH1A1HTTGAAHPGD | |
| SCHEMBL11836425 | 0.78 | F2 (0.44) | KMT2AALDH1A1HTTGAAHPGD | |
| SCHEMBL185767 | 0.78 | PTGES2 (0.53) | KMT2AALDH1A1HTTGAAHPGD | |
| SCHEMBL301650 | 0.78 | KMT2A (0.46) | KMT2AALDH1A1HTTGAAHPGD | |
| SCHEMBL10050617 | 0.78 | L3MBTL1 (0.47) | KMT2AALDH1A1HTTGAAHPGD | |
| SCHEMBL1925734 | 0.78 | KMT2A (0.44) | KMT2AALDH1A1HTTGAAHPGD | |
| SCHEMBL11404135 | 0.78 | KMT2A (0.44) | KMT2AALDH1A1HTTGAAHPGD | |
| SCHEMBL24254279 | 0.76 | KMT2A (0.56) | KMT2AALDH1A1HTTGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1299 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115304543-B | Preparation method and product of aryl sulfonamide containing norbornenyl and application of aryl sulfonamide | 南京林业大学 | 2024-08-20 | — | — | CN | claimed |
| CN-117050053-A | Novel thiophene antitumor compound and preparation method and application thereof | 北京中医药大学 | 2023-11-14 | — | — | CN | claimed |
| CN-115399179-A | Application of polysaccharide-based cationic polymer in prevention and treatment of soil-borne diseases of agriculture and forestry | 中国科学院化学研究所 | 2022-11-29 | — | — | CN | claimed |
| CN-115304543-A | Preparation method of aryl sulfonamide containing norbornenyl, product and application thereof | 南京林业大学 | 2022-11-08 | — | — | CN | claimed |
| WO-2013102936-A1 | N-(3-((DIETHYLAMINO) METHYL)-4-HYDROXYPHENYL)-N-(QUINOLIN-4-YL) SULFONAMIDES FOR THE TREATMENT OF TUBERCULOSIS AND PROCESS OF PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-07-11 | — | — | WO | claimed |
| US-8440844-B2 | Process for the preparation of β-amino alcohol | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-05-14 | — | — | US | claimed |
| EP-1506176-B1 | AMINOINDAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | PFIZER ITALIA SRL (IT) | 2013-04-24 | — | — | EP | claimed |
| US-20120330031-A1 | Process for the Preparation of Beta-Amino Alcohol | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2012-12-27 | — | — | US | claimed |
| US-7838550-B2 | Selective N-sulfonylation of 2-amino fluoro- and trifluoroalkyl substituted alcohols | WYETH LLC (US) | 2010-11-23 | — | — | US | claimed |
| US-7737303-B2 | Production of chirally pure amino alcohol intermediates, derivatives thereof, and uses thereof | WYETH LLC (US) | 2010-06-15 | — | — | US | claimed |
| EP-1984347-A1 | SELECTIVE N-SULFONYLATION OF 2-AMINO TRIFLUOROALKYL SUBSTITUTED ALCOHOLS | Wyeth a Corporation of the State of Delaware (US) | 2008-10-29 | — | — | EP | claimed |
| WO-2007127108-A1 | PRODUCTION OF CHIRALLY PURE AMINO ALCOHOL INTERMEDIATES, DERIVATIVES THEREOF, AND USES THEREOF | WYETH (US) | 2007-11-08 | — | — | WO | claimed |
| US-20070249869-A1 | Production of chirally pure amino alcohol intermediates, derivatives thereof, and uses thereof | WYETH (US) | 2007-10-25 | — | — | US | claimed |
| WO-2007098030-A1 | SELECTIVE N-SULFONYLATION OF 2-AMINO TRIFLUOROALKYL SUBSTITUTED ALCOHOLS | WYETH (US) | 2007-08-30 | — | — | WO | claimed |
| US-20070197800-A1 | Selective n-sulfonylation of 2-amino flouro-and trifluoroalkyl substituted alcohols | WYETH (US) | 2007-08-23 | — | — | US | claimed |
| EP-1377589-B1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | PHARMACIA ITALIA SPA (IT) | 2005-09-07 | — | — | EP | claimed |
| US-6800764-B2 | PREPARING CHIRALLY PURE S-ENANTIOMERS OF ALPHA -AMINO ACIDS COMPRISING THE STEPS OF: A) PREPARING AN ORGANOMETALLIC REAGENT FROM AN ALKYL HALIDE OF THE FORMULA (R) 2CH(CH2)NCH2X; B) ADDING THE ORGANOMETALLIC REAGENT TO CARBON DIOXIDE TO FORM | WYETH | 2004-10-05 | — | — | US | claimed |
| EP-1461303-A2 | PROCESS FOR THE SYNTHESIS OF CHIRALLY PURE b-AMINO-ALCOHOLS | Wyeth (US) | 2004-09-29 | — | — | EP | claimed |
| US-20030144531-A1 | Process for the synthesis of chirally pure beta-amino-alcohols | WYETH (US) | 2003-07-31 | — | — | US | claimed |
| WO-2003050063-A2 | PROCESS FOR THE SYNTHESIS OF CHIRALLY PURE β-AMINO-ALCOHOLS | WYETH (US) | 2003-06-19 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120330031-A1 | Process for the Preparation of Beta-Amino Alcohol | BACE1, BACE2, APP | KMT2A 1681/4885ALDH1A1 24/4885HTT 1844/4885 |
| US-20030144531-A1 | Process for the synthesis of chirally pure beta-amino-alcohols | ADH1C, ADH1A, ALDH7A1 | KMT2A 1629/4885ALDH1A1 189/4885HTT 3711/4885 |
| US-20070197800-A1 | Selective n-sulfonylation of 2-amino flouro-and trifluoroalkyl substituted alcohols | BRAF, AFF2, SELENOI | KMT2A 262/4885ALDH1A1 1532/4885HTT 864/4885 |
| US-20070249869-A1 | Production of chirally pure amino alcohol intermediates, derivatives thereof, and uses thereof | ADH1C, ADH1A, ACMSD | KMT2A 77/4885ALDH1A1 51/4885HTT 1124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.