Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 5/20 | 0.35 |
| ▸ | CA1 | P00915 | 4/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1948943 | 0.82 | CA12 (0.35) | CA12CA14CA2CA1CA7 | |
| SCHEMBL1927057 | 0.78 | CA2 (0.35) | CA12CA14CA2CA1CA7 | |
| SCHEMBL13270349 | 0.77 | CA12 (0.36) | CA12CA14CA2CA1CA7 | |
| SCHEMBL13270350 | 0.77 | TDP1 (0.42) | CA12CA14CA2CA1CA7 | |
| SCHEMBL1927273 | 0.76 | DGAT1 (0.41) | CA12CA14CA2CA1CA7 | |
| SCHEMBL25983374 | 0.74 | MEN1 (0.49) | CA12CA2CA1CA7CA9 | |
| SCHEMBL7519135 | 0.73 | CA1 (0.41) | CA12CA14CA2CA1CA7 | |
| SCHEMBL19931568 | 0.73 | ALDH1A1 (0.44) | CA12CA14CA2CA1CA7 | |
| SCHEMBL1925644 | 0.73 | CA1 (0.42) | CA12CA2CA1CA7CA9 | |
| SCHEMBL1925646 | 0.73 | TDP1 (0.50) | CA12CA2CA1CA9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2509941-A2 | N-ACYLATED HYDROXYLAMINE DERIVATIVES AND O-ACYLATED HYDROXYLAMINE DERIVATIVES | The Johns Hopkins University (US) | 2012-10-17 | — | — | EP | disclosed |
| WO-2011071951-A2 | N-ACYLOXYSULFONAMIDE AND N-HYDROXY-N-ACYLSULFONAMIDE DERIVATIVES | JOHNS HOPKINS UNIVERSITY (US) | 2011-06-16 | — | — | WO | disclosed |