SCHEMBL1928279

SCHEMBL1928279

NCC1(CO)CCCCC1

nearest known ligand 0.54

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.54
ALDH1A1 P00352 1/20 0.54
LMNA P02545 1/20 0.54
CYP1A2 P05177 1/20 0.54
TSHR P16473 1/20 0.54
BLM P54132 1/20 0.54
CACNA2D1 P54289 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
SLC6A3 Q01959 3/20 0.30
SLC6A4 P31645 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4079340 1.00 USP2 (0.54) USP2ALDH1A1LMNACYP1A2TSHR
SCHEMBL4078173 1.00 USP2 (0.54) USP2ALDH1A1LMNACYP1A2TSHR
Hydrochloric Acid SCHEMBL9229306 0.97 USP2 (0.52) USP2ALDH1A1LMNACYP1A2TSHR
SCHEMBL2283858 0.97
SCHEMBL290618 0.92
SCHEMBL290856 0.85
Hydrochloric Acid SCHEMBL15398546 0.82
SCHEMBL302071 0.82 ALDH1A1 (0.39) USP2ALDH1A1LMNACYP1A2TSHR
SCHEMBL4874234 0.82 ALDH1A1 (0.39) USP2ALDH1A1LMNACYP1A2TSHR
SCHEMBL22444527 0.82 ALDH1A1 (0.39) USP2ALDH1A1LMNACYP1A2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116120554-A Composition for optical lens material with high refractive index and low thermal expansion coefficient 益丰新材料股份有限公司 2023-05-16 CN claimed
US-9556117-B2 Indole carboxamide derivatives as P2X7 receptor antagonists ACTELION PHARMACEUTICALS LTD. (CH) 2017-01-31 US claimed
EP-2935211-B1 INDOLE CARBOXAMIDE DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS ACTELION PHARMACEUTICALS LTD (CH) 2016-11-09 EP claimed
US-20150344425-A1 INDOLE CARBOXAMIDE DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS ACTELION PHARMACEUTICALS LTD (CH) 2015-12-03 US claimed
US-12435051-B2 Dual modulator of mGluR5 and 5-HT2A receptor, and use thereof VIVOZON, INC. (KR) 2025-10-07 US disclosed
CN-116120554-B Composition for optical lens material with high refractive index and low thermal expansion coefficient 益丰新材料股份有限公司 2025-03-18 CN disclosed
CN-116234552-B Dual modulators of mGluR5 and 5-HT2A receptors and uses thereof (株)倍宝尊 2025-02-25 CN disclosed
US-20240360092-A1 DUAL MODULATOR OF MGLUR5 AND 5-HT2A RECEPTOR, AND USE THEREOF VIVOZON INC. (KR) 2024-10-31 US disclosed
US-12060339-B2 Dual modulator of mGluR5 and 5-HT2A receptor, and use thereof VIVOZON INC. (KR) 2024-08-13 US disclosed
EP-3365334-B1 BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS OTSUKA PHARMA CO LTD (JP) 2024-07-17 EP disclosed
EP-4190770-A1 DUAL REGULATOR FOR MGLUR5 AND 5-HT2A RECEPTORS AND USE THEREOF Vivozon, Inc. (KR) 2023-06-07 EP disclosed
EP-4190770-A1 DUAL REGULATOR FOR MGLUR5 AND 5-HT2A RECEPTORS AND USE THEREOF Vivozon, Inc. (KR) 2023-06-07 EP disclosed
US-4645802-A MOLDING MATERIALS EASTMAN KODAK COMPANY (US) 1987-02-24 US disclosed
US-4420581-A ANTHRAQUINONE DYE CARBOXYLIC ACID MONOMER EASTMAN KODAK COMPANY (US) 1983-12-13 US disclosed
EP-0009866-B1 PHENOLIC ESTERAMIDE ANTIOXIDANTS AND THEIR USE UNIROYAL, INC. (US) 1982-08-04 EP disclosed
US-4305868-A Phenolic esteramide antioxidants UNIROYAL, INC. (US) 1981-12-15 US disclosed
US-4267306-A FIBER-REACTIVE AND TRIAZOLE DYES; BEVERAGE BOTTLES; POLYAMIDES AND CELLULOSE ESTERS; COLORFASTNESS EASTMAN KODAK COMPANY (US) 1981-05-12 US disclosed
US-4263446-A Process for making 3-(3,5-dialkyl-4-hydroxyphenyl)propionate esters of hydroxyalkyloxamides UNIROYAL, INC. (US) 1981-04-21 US disclosed
US-4250078-A CONTAINING FERRIC OXIDE EASTMAN KODAK COMPANY (US) 1981-02-10 US disclosed
EP-0009866-A1 Phenolic esteramide antioxidants and their use UNIROYAL, INC. (US) 1980-04-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12435051-B2 Dual modulator of mGluR5 and 5-HT2A receptor, and use thereof GRM5, HTR5A, HTR2A USP2 2437/4885ALDH1A1 3972/4885LMNA 4783/4885
US-20240360092-A1 DUAL MODULATOR OF MGLUR5 AND 5-HT2A RECEPTOR, AND USE THEREOF GRM5, HTR5A, HTR2A USP2 2437/4885ALDH1A1 3972/4885LMNA 4783/4885
US-20150344425-A1 INDOLE CARBOXAMIDE DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS P2RX7, P2RX3, P2RX1 USP2 4164/4885ALDH1A1 2019/4885LMNA 2785/4885
US-12060339-B2 Dual modulator of mGluR5 and 5-HT2A receptor, and use thereof GRM5, HTR5A, HTR2A USP2 2437/4885ALDH1A1 3972/4885LMNA 4783/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.