Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 4/20 | 0.35 |
| ▸ | KCNQ3 | O43525 | 3/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | KCNQ4 | P56696 | 2/20 | 0.35 |
| ▸ | KCNQ5 | Q9NR82 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | MTTP | P55157 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19301146 | 0.94 | HDAC1 (0.38) | THRBKCNQ2KCNQ3FAAHKCNQ4 | |
| SCHEMBL23522701 | 0.76 | L3MBTL1 (0.44) | MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL19301144 | 0.75 | FAAH (0.41) | FAAHHDAC1MEN1LMNAKMT2A | |
| SCHEMBL20743034 | 0.71 | PTGS1 (0.44) | KCNQ2NPSR1HDAC1HDAC2MEN1 | |
| SCHEMBL19301143 | 0.71 | FAAH (0.41) | FAAHNPSR1HDAC1MEN1LMNA | |
| SCHEMBL19283479 | 0.70 | PTGS1 (0.48) | KCNQ2HDAC1HDAC2MEN1LMNA | |
| SCHEMBL21821322 | 0.69 | TRPV1 (0.36) | MTTPL3MBTL1 | |
| SCHEMBL19301092 | 0.69 | L3MBTL1 (0.45) | MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL21821315 | 0.68 | PTGS1 (0.44) | KCNQ2HDAC1HDAC2MEN1LMNA | |
| SCHEMBL30814183 | 0.68 | KCNQ2 (0.64) | THRBKCNQ2KCNQ3KCNQ4KCNQ5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210188804-A1 | NOVEL POTASSIUM CHANNEL INHIBITORS | ACESION PHARMA APS (DK) | 2021-06-24 | — | — | US | disclosed |
| US-20210188804-A1 | NOVEL POTASSIUM CHANNEL INHIBITORS | ACESION PHARMA APS (DK) | 2021-06-24 | — | — | US | disclosed |
| EP-3419973-B1 | NOVEL POTASSIUM CHANNEL INHIBITORS | ACESION PHARMA APS (DK) | 2020-04-08 | — | — | EP | disclosed |
| EP-3419973-A1 | NOVEL POTASSIUM CHANNEL INHIBITORS | Acesion Pharma ApS (DK) | 2019-01-02 | — | — | EP | disclosed |
| WO-2017144183-A1 | NOVEL POTASSIUM CHANNEL INHIBITORS | ACESION PHARMA APS (DK) | 2017-08-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210188804-A1 | NOVEL POTASSIUM CHANNEL INHIBITORS | KCNJ2, KCNN2, KCNN1 | THRB 2193/4885KCNQ2 23/4885KCNQ3 42/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.