Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.42 |
| ▸ | ESR1 | P03372 | 3/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30109372 | 0.89 | ALDH1A1 (0.55) | ALOX5ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL19284532 | 0.87 | MAPT (0.51) | ALOX5ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL15238230 | 0.81 | KDR (0.58) | ALOX5ALDH1A1RAB9AATMSMN1; SMN2 | |
| SCHEMBL18960451 | 0.78 | MEN1 (0.50) | MEN1KMT2AESR2ESR1CA12 | |
| SCHEMBL8698788 | 0.77 | PLOD2 (0.56) | ALOX5ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL14881406 | 0.77 | ALOX5 (0.55) | ALOX5ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL19122415 | 0.76 | PCSK9 (0.56) | ALDH1A1MAPTMEN1KMT2AUSP2 | |
| SCHEMBL10144997 | 0.76 | ALOX5 (0.60) | ALOX5ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3097713 | 0.76 | ALOX5 (0.60) | ALOX5ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL14881542 | 0.75 | ALOX5 (0.56) | ALOX5ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017147047-A1 | FXR MODULATORS AND METHODS OF THEIR USE | ALIOS BIOPHARMA, INC. (US) | 2017-08-31 | — | — | WO | disclosed |
| WO-2017147047-A1 | FXR MODULATORS AND METHODS OF THEIR USE | ALIOS BIOPHARMA, INC. (US) | 2017-08-31 | — | — | WO | disclosed |