Phosphoramidic Acid

Phosphoramidic Acid

SCHEMBL19285697

C#CCc1ccccc1.NP(=O)(O)O

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LAP3 P28838 4/20 0.44
ANPEP P15144 4/20 0.44
TSHR P16473 2/20 0.42
ERAP1 Q9NZ08 2/20 0.42
ERAP2 Q6P179 1/20 0.42
FDPS P14324 1/20 0.41
HPGD P15428 1/20 0.39
ACP3 P15309 1/20 0.39
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL27692050 0.83 CES2 (0.46) TSHR
SCHEMBL4243 0.82
SCHEMBL29184894 0.80 TSHR (0.45) TSHR
SCHEMBL28385336 0.80 TSHR (0.45) TSHR
Propiolic Acid SCHEMBL17554270 0.79 CES2 (0.43) TSHR
SCHEMBL16569812 0.76 PYCR1 (0.46) TSHR
Allyl Alcohol SCHEMBL11726889 0.72 TSHR (0.39) TSHR
SCHEMBL6593221 0.71 MAOA (0.38) TSHR
SCHEMBL7194213 0.71 ALDH1A1 (0.54) HPGD
SCHEMBL1764685 0.70 HPGD (0.56) LAP3ANPEPTSHRERAP1ERAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3478363-A1 AMPHETAMINE CONTROLLED RELEASE, PRODRUG, AND ABUSE DETERRENT DOSAGE FORMS Chemapotheca LLC (US) 2019-05-08 EP disclosed
WO-2017147375-A1 AMPHETAMINE CONTROLLED RELEASE, PRODRUG, AND ABUSE DETERRENT DOSAGE FORMS CHEMAPOTHECA, LLC (US) 2017-08-31 WO disclosed