Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | MAX | P61244 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ULK1 | O75385 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 3/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19286197 | 1.00 | MAPT (0.48) | MAPTMEN1KMT2AMYCMAX | |
| SCHEMBL19286299 | 0.91 | HTT (0.42) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL19286235 | 0.91 | HTT (0.42) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL19286195 | 0.89 | KDM4E (0.42) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL19286300 | 0.89 | KDM4E (0.42) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL19286237 | 0.83 | LMNA (0.42) | MAPTMEN1KMT2AMYCMAX | |
| SCHEMBL19286269 | 0.81 | LMNA (0.35) | MAPTMEN1KMT2AMYCMAX | |
| SCHEMBL19286314 | 0.77 | ALPL (0.42) | MEN1KMT2AHTTLMNAGAA | |
| SCHEMBL19286247 | 0.77 | ALPL (0.42) | MEN1KMT2AHTTLMNAGAA | |
| SCHEMBL17470039 | 0.77 | MAPT (0.50) | MAPTMEN1KMT2AMYCMAX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9744528-B2 | Metallorganocatalysis for asymmetric transformations | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-08-29 | — | — | US | disclosed |