Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSPA9 | P38646 | 3/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19286235 | 1.00 | HTT (0.42) | HTTMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL19286193 | 0.91 | MAPT (0.48) | HTTMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL19286197 | 0.91 | MAPT (0.48) | HTTMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL19286300 | 0.80 | KDM4E (0.42) | HTTMEN1KMT2ASMN1; SMN2EPHX2 | |
| SCHEMBL19286195 | 0.80 | KDM4E (0.42) | HTTMEN1KMT2ASMN1; SMN2EPHX2 | |
| SCHEMBL19286247 | 0.78 | ALPL (0.42) | HTTMEN1KMT2ALMNAGAA | |
| SCHEMBL19286314 | 0.78 | ALPL (0.42) | HTTMEN1KMT2ALMNAGAA | |
| SCHEMBL19286217 | 0.74 | LTC4S (0.44) | LMNAEPHX2GAA | |
| SCHEMBL19286237 | 0.74 | LMNA (0.42) | HTTMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL19286267 | 0.73 | ALDH1A1 (0.33) | HTTMEN1KMT2ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9744528-B2 | Metallorganocatalysis for asymmetric transformations | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-08-29 | — | — | US | disclosed |