Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19286314 | 1.00 | ALPL (0.42) | ALPLALPIALPGRECQLLMNA | |
| SCHEMBL19286276 | 0.84 | LMNA (0.30) | LMNAHPGDL3MBTL1 | |
| SCHEMBL19286217 | 0.84 | LTC4S (0.44) | LMNAGAA | |
| SCHEMBL19286267 | 0.79 | ALDH1A1 (0.33) | RECQLLMNAEPHX1HTTKMT2A | |
| SCHEMBL19286197 | 0.77 | MAPT (0.48) | LMNAHTTGAAKMT2AMEN1 | |
| SCHEMBL19286193 | 0.77 | MAPT (0.48) | LMNAHTTGAAKMT2AMEN1 | |
| SCHEMBL19286201 | 0.77 | MEN1 (0.41) | KMT2AMEN1 | |
| SCHEMBL19286279 | 0.74 | L3MBTL1 (0.32) | GAAL3MBTL1 | |
| SCHEMBL19286232 | 0.72 | TRPA1 (0.33) | L3MBTL1 | |
| SCHEMBL19286245 | 0.72 | TRPA1 (0.33) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9744528-B2 | Metallorganocatalysis for asymmetric transformations | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-08-29 | — | — | US | disclosed |