Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13586986 | 0.83 | SMN1; SMN2 (0.39) | SMN1; SMN2CHRNA7ACHETDP1TAS1R3 | |
| SCHEMBL178538 | 0.79 | ALDH1A1 (0.52) | SMN1; SMN2CHRNA7ACHETDP1TAS1R3 | |
| SCHEMBL19286210 | 0.79 | ADRB2 (0.54) | SMN1; SMN2TDP1LMNAALDH1A1HPGD | |
| SCHEMBL8284259 | 0.79 | ALDH1A1 (0.52) | SMN1; SMN2CHRNA7ACHETDP1TAS1R3 | |
| SCHEMBL8285887 | 0.79 | ALDH1A1 (0.52) | SMN1; SMN2CHRNA7ACHETDP1TAS1R3 | |
| SCHEMBL6114224 | 0.77 | SMN1; SMN2 (0.41) | SMN1; SMN2CHRNA7ACHETDP1TAS1R3 | |
| SCHEMBL2663534 | 0.77 | LMNA (0.41) | SMN1; SMN2CHRNA7ACHETDP1TAS1R3 | |
| SCHEMBL7773053 | 0.77 | SMN1; SMN2 (0.41) | SMN1; SMN2CHRNA7ACHETDP1TAS1R3 | |
| SCHEMBL8278972 | 0.77 | SMN1; SMN2 (0.41) | SMN1; SMN2CHRNA7ACHETDP1TAS1R3 | |
| SCHEMBL14305054 | 0.77 | SMN1; SMN2 (0.41) | SMN1; SMN2CHRNA7ACHETDP1TAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9744528-B2 | Metallorganocatalysis for asymmetric transformations | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-08-29 | — | — | US | disclosed |