Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 10/20 | 0.54 |
| ▸ | F13A1 | P00488 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SCD | O00767 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19292317 | 0.83 | TBXAS1 (0.42) | TBXAS1 | |
| Acetic Acid SCHEMBL21996138 | 0.79 | BRS3 (0.43) | MAPTALDH1A1CYP1A2LMNATSHR | |
| SCHEMBL3186205 | 0.78 | GPR84 (0.42) | ALDH1A1 | |
| SCHEMBL6251513 | 0.73 | HRH3 (0.38) | ALDH1A1 | |
| SCHEMBL5296032 | 0.71 | MAPT (0.55) | TBXAS1F13A1MAPTRXFP1 | |
| SCHEMBL1091991 | 0.70 | TBXAS1 (1.00) | TBXAS1F13A1MAPTRXFP1LMNA | |
| SCHEMBL11009198 | 0.70 | TBXAS1 (1.00) | TBXAS1F13A1MAPTRXFP1LMNA | |
| SCHEMBL28703772 | 0.70 | TBXAS1 (1.00) | TBXAS1F13A1MAPTRXFP1LMNA | |
| SCHEMBL1460951 | 0.70 | TBXAS1 (1.00) | TBXAS1F13A1MAPTRXFP1LMNA | |
| SCHEMBL7051672 | 0.70 | TBXAS1 (1.00) | TBXAS1F13A1MAPTRXFP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2914589-B1 | COMPOUNDS FOR USE IN THE TREATMENT OF PARASITIC DISEASES | IRBM - SCIENCE PARK S P A (IT) | 2017-08-30 | — | — | EP | disclosed |