Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM6B | O15054 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6251513 | 0.89 | HRH3 (0.38) | BRS3KDM4EPKMMEN1ALDH1A1 | |
| SCHEMBL11874825 | 0.84 | PI4KA (0.41) | PKMALDH1A1GPR84 | |
| SCHEMBL3186205 | 0.82 | GPR84 (0.42) | PKMALDH1A1GPR84 | |
| SCHEMBL7680733 | 0.82 | GPR84 (0.42) | PKMALDH1A1GPR84 | |
| SCHEMBL27374286 | 0.78 | BRS3 (0.47) | BRS3KDM4EPKMMEN1ALDH1A1 | |
| SCHEMBL24445917 | 0.78 | — | — | |
| SCHEMBL2763630 | 0.73 | MMP2 (0.41) | BRS3KDM4EPKMMEN1ALDH1A1 | |
| SCHEMBL27454468 | 0.73 | MMP2 (0.48) | BRS3KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL19292317 | 0.72 | TBXAS1 (0.42) | — | |
| SCHEMBL8319666 | 0.72 | CYP3A4 (0.48) | BRS3CYP1A2CYP3A4KDM6BKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12303876-B2 | Methods for cellulose hydrolysis using sulfonated polyaromatic catalysts | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2025-05-20 | — | — | US | disclosed |
| US-20220001367-A1 | METHODS FOR CELLULOSE HYDROLYSIS USING SULFONATED POLYAROMATIC CATALYSTS | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2022-01-06 | — | — | US | disclosed |
| WO-2020112701-A1 | METHODS FOR CELLULOSE HYDROLYSIS USING SULFONATED POLYAROMATIC CATALYSTS | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2020-06-04 | — | — | WO | disclosed |