SCHEMBL19299281

SCHEMBL19299281

c1ccc(-c2ccc(-c3cccc(-c4cccc5c4Oc4ccccc4C54c5ccccc5-c5ccccc54)c3)nn2)cc1

nearest known ligand 0.32

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.32
NPC1 O15118 2/20 0.31
PKM P14618 2/20 0.31
RAB9A P51151 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
MAPT P10636 1/20 0.31
MAOB P27338 1/20 0.31
AGTR1 P30556 1/20 0.31
SMARCA2 P51531 1/20 0.31
SMARCA4 P51532 1/20 0.31
PBRM1 Q86U86 1/20 0.31
NPY5R Q15761 1/20 0.31
USP2 O75604 1/20 0.31
TP53 P04637 1/20 0.31
THRB P10828 1/20 0.30
PDK2 Q15119 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21677479 0.95 BACE1 (0.31) BACE1NPC1PKMRAB9ASMN1; SMN2
SCHEMBL21677976 0.95 PDK2 (0.36) BACE1NPC1PKMRAB9ASMN1; SMN2
SCHEMBL21677689 0.92 SMARCA2 (0.33) BACE1NPC1PKMRAB9ASMN1; SMN2
SCHEMBL19298386 0.91 NPC1 (0.33) NPC1PKMRAB9ASMN1; SMN2MAPT
SCHEMBL20622522 0.89 KDM4E (0.33) RAB9ASMN1; SMN2MAPTTP53
SCHEMBL21578209 0.88 PARP1 (0.34) BACE1RAB9ATHRB
SCHEMBL20618970 0.88 MAPT (0.39) BACE1SMN1; SMN2MAPTMAOBAGTR1
SCHEMBL21677706 0.88 BACE1 (0.34) BACE1NPC1PKMRAB9ASMN1; SMN2
SCHEMBL24647644 0.87 THRB (0.36) BACE1RAB9AMAPTTHRBPDK2
SCHEMBL19299319 0.87 MAPT (0.39) BACE1SMN1; SMN2MAPTMAOBAGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230024114-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2023-01-26 US disclosed
US-20220376178-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2022-11-24 US disclosed
US-11152576-B2 Organic light emitting device LG CHEM, LTD. (KR) 2021-10-19 US disclosed
US-20210288264-A1 Heterocyclic Compound And Organic Light Emitting Element Comprising Same LG CHEM, LTD. (KR) 2021-09-16 US disclosed
US-11094889-B2 Heterocyclic compound and organic light emitting element comprising same LG CHEM, LTD. 2021-08-17 US disclosed
US-20210013422-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2021-01-14 US disclosed
US-20200365814-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2020-11-19 US disclosed
US-20200035930-A1 ORGANIC LIGHT EMITTING ELEMENT LG CHEM, LTD. (KR) 2020-01-30 US disclosed
WO-2019004787-A1 ORGANIC LIGHT EMITTING ELEMENT 주식회사 엘지화학 2019-01-03 WO disclosed
WO-2017146466-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME 주식회사 엘지화학 2017-08-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210288264-A1 Heterocyclic Compound And Organic Light Emitting Element Comprising Same CRY1, CRY2, PER2 BACE1 616/4885NPC1 3631/4885PKM 3850/4885
US-11094889-B2 Heterocyclic compound and organic light emitting element comprising same CRY1, CRY2, PER2 BACE1 616/4885NPC1 3631/4885PKM 3850/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.