Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.67 |
| ▸ | MAPT | P10636 | 11/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.67 |
| ▸ | HTT | P42858 | 7/20 | 0.67 |
| ▸ | LMNA | P02545 | 6/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.67 |
| ▸ | MEN1 | O00255 | 13/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 13/20 | 0.62 |
| ▸ | POLB | P06746 | 7/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | RECQL | P46063 | 5/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 6/20 | 0.58 |
| ▸ | THRB | P10828 | 2/20 | 0.58 |
| ▸ | CRHBP | P24387 | 1/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19299511 | 0.87 | ALDH1A1 (0.67) | ALDH1A1MAPTKDM4EHTTLMNA | |
| SCHEMBL19299643 | 0.81 | KDM4E (1.00) | ALDH1A1MAPTKDM4EHTTLMNA | |
| SCHEMBL19294530 | 0.80 | KDM4E (0.56) | ALDH1A1MAPTKDM4EHTTLMNA | |
| SCHEMBL14825292 | 0.74 | ALDH1A1 (1.00) | ALDH1A1MAPTKDM4EHTTLMNA | |
| SCHEMBL21416971 | 0.70 | KDM4E (1.00) | ALDH1A1MAPTKDM4EHTTLMNA | |
| SCHEMBL6721022 | 0.69 | KMT2A (1.00) | ALDH1A1MAPTKDM4EHTTLMNA | |
| SCHEMBL19299523 | 0.68 | KDM4E (0.73) | ALDH1A1MAPTKDM4EHTTLMNA | |
| SCHEMBL19294541 | 0.68 | KDM4E (0.80) | ALDH1A1MAPTKDM4EHTTLMNA | |
| SCHEMBL14096448 | 0.68 | KMT2A (0.79) | ALDH1A1MAPTKDM4EHTTLMNA | |
| SCHEMBL11869994 | 0.67 | NOTUM (0.67) | ALDH1A1MAPTKDM4EHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3212183-B1 | SYNERGISTIC COMPOSITIONS FOR TREATING MICROBIAL INFECTIONS | UNIV ROCHESTER (US) | 2019-10-02 | — | — | EP | disclosed |
| US-10028931-B2 | Synergistic compositions for treating microbial infections | UNIVERSITY OF ROCHESTER (US) | 2018-07-24 | — | — | US | disclosed |
| US-20170246139-A1 | SYNERGISTIC COMPOSITIONS FOR TREATING MICROBIAL INFECTIONS | UNIVERSITY OF ROCHESTER (US) | 2017-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10028931-B2 | Synergistic compositions for treating microbial infections | RNASE1, RNASEL, RNASEH1 | ALDH1A1 3822/4885MAPT 4406/4885KDM4E 2925/4885 |
| US-20170246139-A1 | SYNERGISTIC COMPOSITIONS FOR TREATING MICROBIAL INFECTIONS | RNASE1, RNASEL, RNASEH1 | ALDH1A1 3822/4885MAPT 4406/4885KDM4E 2925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.