Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | UBE2N | P61088 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19299709 | 0.83 | UBE2N (0.52) | POLBTDP1MAPTKMT2AL3MBTL1 | |
| SCHEMBL12697080 | 0.81 | KDM4E (0.74) | TDP1MAPTKMT2AUBE2NALDH1A1 | |
| SCHEMBL19294529 | 0.81 | UBE2N (0.60) | TDP1MAPTKMT2AUBE2NALDH1A1 | |
| SCHEMBL19294545 | 0.80 | ALDH1A1 (0.57) | TDP1MAPTKMT2AUBE2NALDH1A1 | |
| SCHEMBL19294528 | 0.80 | MEN1 (0.61) | TDP1MAPTKMT2AUBE2NALDH1A1 | |
| SCHEMBL19299653 | 0.79 | UBE2N (0.53) | TDP1MAPTKMT2AUBE2NALDH1A1 | |
| SCHEMBL19299380 | 0.78 | UBE2N (0.55) | TDP1MAPTKMT2AHPGDUBE2N | |
| SCHEMBL19299706 | 0.78 | UBE2N (0.55) | MAPTKMT2AUBE2NALDH1A1 | |
| SCHEMBL19299537 | 0.78 | UBE2N (0.54) | TDP1MAPTKMT2AHPGDUBE2N | |
| SCHEMBL19299644 | 0.78 | UBE2N (0.54) | TDP1MAPTKMT2AUBE2NALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3212183-B1 | SYNERGISTIC COMPOSITIONS FOR TREATING MICROBIAL INFECTIONS | UNIV ROCHESTER (US) | 2019-10-02 | — | — | EP | disclosed |
| US-10028931-B2 | Synergistic compositions for treating microbial infections | UNIVERSITY OF ROCHESTER (US) | 2018-07-24 | — | — | US | disclosed |
| US-20170246139-A1 | SYNERGISTIC COMPOSITIONS FOR TREATING MICROBIAL INFECTIONS | UNIVERSITY OF ROCHESTER (US) | 2017-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10028931-B2 | Synergistic compositions for treating microbial infections | RNASE1, RNASEL, RNASEH1 | POLB 340/4885TDP1 448/4885MAPT 4406/4885 |
| US-20170246139-A1 | SYNERGISTIC COMPOSITIONS FOR TREATING MICROBIAL INFECTIONS | RNASE1, RNASEL, RNASEH1 | POLB 340/4885TDP1 448/4885MAPT 4406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.