Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.90 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.90 |
| ▸ | LMNA | P02545 | 1/20 | 0.90 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.90 |
| ▸ | TSHR | P16473 | 1/20 | 0.90 |
| ▸ | ACHE | P22303 | 1/20 | 0.90 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.90 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.90 |
| ▸ | CHRNA7 | P36544 | 15/20 | 0.51 |
| ▸ | CHRNB4 | P30926 | 11/20 | 0.51 |
| ▸ | CHRNA3 | P32297 | 11/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 9/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 9/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gallamine SCHEMBL12638600 | 0.95 | CHRM2 (1.00) | CHRM2ALOX15LMNACHRM1TSHR | |
| Gallamine SCHEMBL249090 | 0.93 | CHRM2 (1.00) | CHRM2ALOX15LMNACHRM1TSHR | |
| Gallamine SCHEMBL1736255 | 0.88 | CHRM2 (0.87) | CHRM2ALOX15LMNACHRM1TSHR | |
| SCHEMBL8557526 | 0.85 | LMNA (0.62) | CHRM2ALOX15LMNACHRM1TSHR | |
| SCHEMBL16884476 | 0.83 | CHRM2 (0.77) | CHRM2ALOX15LMNACHRM1TSHR | |
| SCHEMBL10879423 | 0.77 | LMNA (0.53) | CHRM2ALOX15LMNACHRM1TSHR | |
| SCHEMBL1238407 | 0.75 | LMNA (0.60) | CHRM2ALOX15LMNACHRM1TSHR | |
| SCHEMBL25205933 | 0.73 | CHRM2 (0.49) | CHRM2ALOX15LMNACHRM1TSHR | |
| SCHEMBL19510572 | 0.73 | CHRM2 (0.49) | CHRM2ALOX15LMNACHRM1TSHR | |
| SCHEMBL1837129 | 0.73 | LMNA (0.49) | CHRM2ALOX15LMNACHRM1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170246180-A1 | ACYCLIC CUCURBIT[N]URIL TYPE MOLECULAR CONTAINERS TO TREAT INTOXICATION AND DECREASE RELAPSE RATE IN SUBSTANCE ABUSE DISORDERS | GENERAL HOSPITAL CORPORATION | 2017-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170246180-A1 | ACYCLIC CUCURBIT[N]URIL TYPE MOLECULAR CONTAINERS TO TREAT INTOXICATION AND DECREASE RELAPSE RATE IN SUBSTANCE ABUSE DISORDERS | CNR1, CNR2, OPRM1 | CHRM2 1069/4885ALOX15 3066/4885LMNA 3286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.