Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.77 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.77 |
| ▸ | LMNA | P02545 | 1/20 | 0.77 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.77 |
| ▸ | TSHR | P16473 | 1/20 | 0.77 |
| ▸ | ACHE | P22303 | 1/20 | 0.77 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.77 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.77 |
| ▸ | CHRNA7 | P36544 | 15/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 11/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 11/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 9/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 9/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gallamine SCHEMBL12638600 | 0.87 | CHRM2 (1.00) | CHRM2ALOX15LMNACHRM1TSHR | |
| Gallamine SCHEMBL249090 | 0.86 | CHRM2 (1.00) | CHRM2ALOX15LMNACHRM1TSHR | |
| SCHEMBL19300483 | 0.83 | CHRM2 (0.90) | CHRM2ALOX15LMNACHRM1TSHR | |
| Gallamine SCHEMBL1736255 | 0.81 | CHRM2 (0.87) | CHRM2ALOX15LMNACHRM1TSHR | |
| SCHEMBL8557526 | 0.67 | LMNA (0.62) | CHRM2ALOX15LMNACHRM1TSHR | |
| SCHEMBL3265285 | 0.67 | CHRM2 (0.59) | CHRM2ALOX15LMNACHRM1TSHR | |
| SCHEMBL1238407 | 0.66 | LMNA (0.60) | CHRM2ALOX15LMNACHRM1TSHR | |
| SCHEMBL13658189 | 0.64 | LMNA (0.58) | CHRM2ALOX15LMNACHRM1TSHR | |
| SCHEMBL13385235 | 0.63 | CHRNA7 (1.00) | ALOX15CHRNA7CHRNB4CHRNA3CHRNB2 | |
| SCHEMBL453505 | 0.63 | CHRM2 (0.56) | CHRM2ALOX15LMNACHRM1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150191430-A1 | CONJUGATES OF HUPERZINE AND ANALOGS THEREOF | BISCAYNE NEUROTHERAPEUTICS, INC. | 2015-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150191430-A1 | CONJUGATES OF HUPERZINE AND ANALOGS THEREOF | HTT, HNMT, GAP43 | CHRM2 1699/4885ALOX15 686/4885LMNA 748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.