Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | MPO | P05164 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | CYP21A2 | P08686 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | AGXT | P21549 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 2/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL20742875 | 0.98 | MAOB (0.49) | SLC6A4MPOMAOBCYP17A1CYP21A2 | |
| SCHEMBL20757828 | 0.87 | MAOB (0.40) | SLC6A4MPOMAOBCYP17A1CYP21A2 | |
| SCHEMBL20757213 | 0.83 | MAOB (0.37) | SLC6A4MPOMAOBCYP17A1CYP21A2 | |
| SCHEMBL19300924 | 0.80 | MPO (0.34) | SLC6A4MPOMAOB | |
| SCHEMBL19300674 | 0.74 | MAOB (0.39) | SLC6A4MPOMAOBCYP17A1CYP21A2 | |
| Hydrochloric Acid SCHEMBL20742869 | 0.73 | MAOB (0.41) | SLC6A4MPOMAOBTAAR1SIGMAR1 | |
| SCHEMBL23824820 | 0.71 | RAB9A (0.39) | SLC6A4MPOMAOBCYP17A1CYP21A2 | |
| SCHEMBL12551571 | 0.71 | AGXT (0.46) | MAOBCYP17A1CYP21A2CYP11B1AGXT | |
| SCHEMBL19300892 | 0.70 | MAOB (0.37) | SLC6A4MPOMAOBAGXTTAAR1 | |
| SCHEMBL2944704 | 0.69 | BCL2L1 (0.48) | MAOBCYP11B1AGXTTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10836706-B2 | Bacterial efflux pump inhibitors | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2020-11-17 | — | — | US | disclosed |
| US-20190055188-A1 | BACTERIAL EFFLUX PUMP INHIBITORS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2019-02-21 | — | — | US | disclosed |
| WO-2017147335-A1 | BACTERIAL EFFLUX PUMP INHIBITORS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-08-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10836706-B2 | Bacterial efflux pump inhibitors | ABCB11, ABCB1, SLC47A1 | SLC6A4 391/4885MPO 1700/4885MAOB 950/4885 |
| US-20190055188-A1 | BACTERIAL EFFLUX PUMP INHIBITORS | ABCB11, ABCB1, SLC47A1 | SLC6A4 391/4885MPO 1700/4885MAOB 950/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.