Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.45 |
| ▸ | MEN1 | O00255 | 9/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.38 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.38 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29380022 | 0.84 | TYMS (0.39) | MAPTMEN1KMT2ATDP1RAB9A | |
| SCHEMBL5120606 | 0.84 | TYMS (0.39) | MAPTMEN1KMT2ATDP1RAB9A | |
| SCHEMBL5120598 | 0.84 | TYMS (0.39) | MAPTMEN1KMT2ATDP1RAB9A | |
| SCHEMBL19301043 | 0.84 | TYMS (0.39) | MAPTMEN1KMT2ATDP1RAB9A | |
| SCHEMBL19301122 | 0.77 | G6PC1 (0.49) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL14385523 | 0.75 | PTGS2 (0.42) | MAPTTDP1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL14386176 | 0.72 | TYMS (0.42) | TDP1ALDH1A1HPGDKDM4EL3MBTL1 | |
| SCHEMBL28045547 | 0.71 | MAPT (0.55) | MAPTMEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL1702594 | 0.70 | MEN1 (0.51) | MAPTMEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL28045461 | 0.70 | MEN1 (0.51) | MAPTMEN1KMT2ATDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3915970-A1 | AROMATIC COMPOUNDS FROM FURANICS | Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO (NL) | 2021-12-01 | — | — | EP | disclosed |
| EP-3419957-B1 | AROMATIC COMPOUNDS FROM FURANICS | TNO (NL) | 2021-09-29 | — | — | EP | disclosed |
| US-10562875-B2 | Aromatic compounds from furanics | NEDERLANDSE ORGANISAITE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 2020-02-18 | — | — | US | disclosed |
| US-20190023678-A1 | AROMATIC COMPOUNDS FROM FURANICS | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 2019-01-24 | — | — | US | disclosed |
| WO-2017146581-A1 | AROMATIC COMPOUNDS FROM FURANICS | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 2017-08-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190023678-A1 | AROMATIC COMPOUNDS FROM FURANICS | PAH, AOX1, TYR | MAPT 3857/4885MEN1 2671/4885KMT2A 2143/4885 |
| US-10562875-B2 | Aromatic compounds from furanics | PAH, AOX1, TYR | MAPT 3857/4885MEN1 2671/4885KMT2A 2143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.