SCHEMBL1930199

SCHEMBL1930199

c1ccc(O[SiH](c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.43
TSHR P16473 1/20 0.43
CA4 P22748 1/20 0.39
KCNA3 P22001 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CA5A P35218 1/20 0.35
CA5B Q9Y2D0 1/20 0.35
NR1H2 P55055 1/20 0.33
BAX Q07812 1/20 0.33
MAOA P21397 1/20 0.33
ALDH1A1 P00352 2/20 0.32
TAAR1 Q96RJ0 1/20 0.32
RECQL P46063 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
SRC P12931 1/20 0.32
SRD5A2 P31213 1/20 0.31
PKM P14618 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL94673 0.84 TDP1 (0.30) TDP1L3MBTL1
SCHEMBL15368875 0.79 L3MBTL1 (0.34) TDP1L3MBTL1ALDH1A1
SCHEMBL28505226 0.79 SLC6A2 (0.36) LTA4HTSHR
SCHEMBL6916437 0.78 LTA4H (0.43) LTA4HTSHRCA4KCNA3TDP1
SCHEMBL707987 0.74 CA4 (0.42) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL14695259 0.74 LTA4H (0.39) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL27545722 0.74 LTA4H (0.39) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL1696542 0.74 LTA4H (0.39) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL28149843 0.74 LTA4H (0.39) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL11415511 0.74 LTA4H (0.39) LTA4HTSHRCA4KCNA3CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2019106-B1 (Thio)Phenoxy Phenyl Silane Composition And Method For Making Same ROHM & HAAS (US) 2013-11-27 EP claimed
CN-101392004-B (thio)phenoxy phenyl silane composition and method for making same ROHM & HAAS 2011-10-12 CN claimed
US-7956125-B2 (Thio)phenoxy phenyl silane compostion and method for making same ROHM AND HAAS COMPANY (US) 2011-06-07 US claimed
CN-101392004-A (thio)phenoxy phenyl silane composition and method for making same ROHM & HAAS (US) 2009-03-25 CN claimed
US-20090039313-A1 (Thio)phenoxy phenyl silane compostion and method for making same ROHM AND HAAS COMPANY (US) 2009-02-12 US claimed
EP-2019106-A1 (Thio)Phenoxy Phenyl Silane Composition And Method For Making Same Rohm and Haas Company (US) 2009-01-28 EP claimed
EP-3507104-B1 PRODUCTION OF CIS-1,4-POLYDIENES WITH MULTIPLE SILANE FUNCTIONAL GROUPS PREPARED BYIN-SITU BRIDGESTONE CORP (JP) 2024-03-27 EP disclosed
EP-4056604-B1 METHOD FOR PRODUCING COPOLYMER OF 1,3,7-OCTATRIENE AND STYRENE KURARAY CO (JP) 2023-08-02 EP disclosed
EP-3564280-B1 COPOLYMER OF 1, 3, 7-OCTATRIENE AND STYRENE AND HYDRIDE THEREOF KURARAY CO (JP) 2023-07-26 EP disclosed
EP-4163311-A1 COPOLYMER OF 1,3,7-OCTATRIENE AND ISOPRENE, HYDRIDE THEREOF, AND METHOD FOR PRODUCING SAID COPOLYMER Kuraray Co., Ltd. (JP) 2023-04-12 EP disclosed
EP-4163312-A1 COPOLYMER OF 1,3,7-OCTATRIENE AND ISOPRENE, HYDRIDE THEREOF, AND METHOD FOR PRODUCING SAID COPOLYMER Kuraray Co., Ltd. (JP) 2023-04-12 EP disclosed
EP-3564274-B1 1, 3, 7-OCTATRIENE POLYMER, HYDRIDE THEREOF, AND METHOD FOR PRODUCING SAID POLYMER KURARAY CO (JP) 2022-12-28 EP disclosed
EP-4056604-A1 METHOD FOR PRODUCING COPOLYMER OF 1,3,7-OCTATRIENE AND STYRENE Kuraray Co., Ltd. (JP) 2022-09-14 EP disclosed
CN-102790141-A Method of making light emitting diodes ROHM & HAAS ELECT MAT 2012-11-21 CN disclosed
CN-101392004-B (thio)phenoxy phenyl silane composition and method for making same ROHM & HAAS 2011-10-12 CN disclosed
US-7956125-B2 (Thio)phenoxy phenyl silane compostion and method for making same ROHM AND HAAS COMPANY (US) 2011-06-07 US disclosed
US-20090146324-A1 Phenoxyphenyl polysiloxane composition and method for making and using same ROHM AND HAAS COMPANY (US) 2009-06-11 US disclosed
CN-101392004-A (thio)phenoxy phenyl silane composition and method for making same ROHM & HAAS (US) 2009-03-25 CN disclosed
US-20090039313-A1 (Thio)phenoxy phenyl silane compostion and method for making same ROHM AND HAAS COMPANY (US) 2009-02-12 US disclosed
EP-2019106-A1 (Thio)Phenoxy Phenyl Silane Composition And Method For Making Same Rohm and Haas Company (US) 2009-01-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090039313-A1 (Thio)phenoxy phenyl silane compostion and method for making same TPMT, TTR, TST LTA4H 671/4885TSHR 3707/4885CA4 4106/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.