SCHEMBL707987

SCHEMBL707987

C[SiH](Oc1ccccc1)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA4 P22748 1/20 0.42
LTA4H P09960 5/20 0.39
TSHR P16473 1/20 0.39
KCNH2 Q12809 1/20 0.33
KCNA3 P22001 1/20 0.33
TRPA1 O75762 1/20 0.32
MAPK1 P28482 1/20 0.32
CA5A P35218 1/20 0.32
CA5B Q9Y2D0 1/20 0.32
HTR1B P28222 2/20 0.31
LMNA P02545 1/20 0.31
HTR1D P28221 1/20 0.31
NR1H2 P55055 1/20 0.31
BAX Q07812 1/20 0.31
MAOA P21397 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15274214 0.87 ACHE (0.40) CA4LTA4HTSHRLMNA
SCHEMBL12191026 0.82 ACHE (0.44) TSHRMAPK1LMNA
SCHEMBL310041 0.76 CA4 (0.48) CA4LTA4HTSHRKCNA3CA5A
SCHEMBL1147891 0.76 CA4 (0.35) CA4LTA4HTSHRTRPA1MAPK1
SCHEMBL2354326 0.76 CA4 (0.48) CA4LTA4HTSHRKCNA3CA5A
SCHEMBL17328006 0.76 CA4 (0.35) CA4LTA4HTSHRTRPA1MAPK1
SCHEMBL704521 0.75 RELA (0.38) CA4LTA4HTSHRKCNH2
SCHEMBL5400858 0.74 KCNA3 (0.50) LTA4HKCNA3HTR1BHTR1D
SCHEMBL1930199 0.74 LTA4H (0.43) CA4LTA4HTSHRKCNH2KCNA3
SCHEMBL6916437 0.74 LTA4H (0.43) CA4LTA4HTSHRKCNH2KCNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3507104-B1 PRODUCTION OF CIS-1,4-POLYDIENES WITH MULTIPLE SILANE FUNCTIONAL GROUPS PREPARED BYIN-SITU BRIDGESTONE CORP (JP) 2024-03-27 EP disclosed
US-20230357511-A1 PRODUCTION METHOD FOR POLYSILOXANE, COMPOSITION INCLUDING POLYSILOXANE, AND MOLDED BODY MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-11-09 US disclosed
US-20230331925-A1 THERMOPLASTIC RESIN, COMPOSITION, MOLDED ARTICLE, OPTICAL LENS, AND METHOD FOR PRODUCING THERMOPLASTIC RESIN MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-10-19 US disclosed
WO-2023171578-A1 THERMOPLASTIC RESIN, METHOD FOR PRODUCING SAME, THERMOPLASTIC RESIN COMPOSITION AND MOLDED BODY 三菱瓦斯化学株式会社 2023-09-14 WO disclosed
EP-4219590-A1 PRODUCTION METHOD FOR POLYSILOXANE, COMPOSITION INCLUDING POLYSILOXANE, AND MOLDED BODY MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-08-02 EP disclosed
EP-4219589-A1 THERMOPLASTIC RESIN, COMPOSITION, MOLDED ARTICLE, OPTICAL LENS, AND METHOD FOR PRODUCING THERMOPLASTIC RESIN MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-08-02 EP disclosed
CN-115926169-A Method for producing polycarbonate copolymer and polysiloxane compound, polycarbonate copolymer, polysiloxane compound, composition, and molded article 三菱瓦斯化学株式会社 2023-04-07 CN disclosed
CN-113614144-B Method for producing polycarbonate copolymer and polysiloxane compound, polycarbonate copolymer, polysiloxane compound, composition, and molded article 三菱瓦斯化学株式会社 2023-03-28 CN disclosed
WO-2022065331-A1 PRODUCTION METHOD FOR POLYSILOXANE, COMPOSITION INCLUDING POLYSILOXANE, AND MOLDED BODY 三菱瓦斯化学株式会社 2022-03-31 WO disclosed
WO-2022065329-A1 THERMOPLASTIC RESIN, COMPOSITION, MOLDED ARTICLE, OPTICAL LENS, AND METHOD FOR PRODUCING THERMOPLASTIC RESIN 三菱瓦斯化学株式会社 2022-03-31 WO disclosed
CN-113614144-A Method for producing polycarbonate copolymer and polysiloxane compound, polycarbonate copolymer, polysiloxane compound, composition, and molded article 三菱瓦斯化学株式会社 2021-11-05 CN disclosed
US-10975178-B2 Production of cis-1,4-polydienes with multiple silane functional groups prepared by in-situ hydrosilylation of polymer cement BRIDGESTONE CORPORATION (JP) 2021-04-13 US disclosed
WO-2020196343-A1 METHODS FOR PRODUCING POLYCARBONATE COPOLYMER AND POLYSILOXANE COMPOUND, POLYCARBONATE COPOLYMER, POLYSILOXANE COMPOUND, COMPOSITION AND MOLDED BODY 三菱瓦斯化学株式会社 2020-10-01 WO disclosed
US-20190211120-A1 Production Of Cis-1,4-Polydienes With Multiple Silane Functional Groups Prepared By In-Situ Hydrosilylation Of Polymer Cement BRIDGESTONE CORPORATION (JP) 2019-07-11 US disclosed
EP-3507104-A1 PRODUCTION OF CIS-1,4-POLYDIENES WITH MULTIPLE SILANE FUNCTIONAL GROUPS PREPARED BYIN-SITU Bridgestone Corporation (JP) 2019-07-10 EP disclosed
WO-2018045291-A1 PRODUCTION OF CIS-1,4-POLYDIENES WITH MULTIPLE SILANE FUNCTIONAL GROUPS PREPARED BY IN-SITU HYDROSILYLATION OF POLYMER CEMENT BRIDGESTONE CORPORATION (JP) 2018-03-08 WO disclosed
US-8124239-B2 Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same FUJITSU LIMITED (JP) 2012-02-28 US disclosed
US-20100155121-A1 SILICA FILM FORMING MATERIAL, SILICA FILM AND METHOD OF MANUFACTURING THE SAME, MULTILAYER WIRING STRUCTURE AND METHOD OF MANUFACTURING THE SAME, AND SEMICONDUCTOR DEVICE AND METHOD OF MANUFACTURING THE SAME FUJITSU LIMITED (JP) 2010-06-24 US disclosed
US-7659357-B2 Precursor organosilicon polymer of 1,2-Bis(dimethylethoxysilyl)ethane, 1,4-bis(dimethylethoxysilyl)benzene, tetraethoxysilane, methyltriethoxysilane, phenyltriethoxysilane; dielectric (DE) films having etching/chemical/moisture resistance; adhesion; low DE constant; minimal wiring delay; high speed FUJITSU LIMITED (JP) 2010-02-09 US disclosed
US-20070026689-A1 Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same FUJITSU LIMITED (JP) 2007-02-01 US disclosed