Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CASP2 | P42575 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23179898 | 0.86 | ALDH1A1 (0.38) | ALDH1A1KMT2AHPGDSMN1; SMN2TP53 | |
| SCHEMBL23253739 | 0.85 | PAOX (0.45) | ADRA1APAOXALDH1A1KMT2AHPGD | |
| SCHEMBL12173943 | 0.84 | SMN1; SMN2 (0.53) | ADRA1APAOXALDH1A1KMT2AHPGD | |
| SCHEMBL13450103 | 0.83 | CASP2 (0.56) | CASP2NAAASMN1; SMN2EPHX2FAAH | |
| SCHEMBL10074561 | 0.82 | NOD1 (0.45) | ADRA1APAOXKMT2ACASP2KDM4E | |
| SCHEMBL23585102 | 0.81 | SMN1; SMN2 (0.41) | ADRA1APAOXALDH1A1KMT2AHPGD | |
| SCHEMBL19703660 | 0.80 | FNTA (0.44) | ALDH1A1KMT2AHPGDCASP2NAAA | |
| SCHEMBL27266013 | 0.80 | ALDH1A1 (0.34) | ALDH1A1KMT2AHPGDSMN1; SMN2TP53 | |
| SCHEMBL25918071 | 0.80 | CASP2 (0.44) | ADRA1APAOXALDH1A1KMT2AHPGD | |
| SCHEMBL12495987 | 0.79 | CASP2 (0.46) | ALDH1A1KMT2AHPGDCASP2NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170247412-A1 | TARGETED DELIVERY OF TERTIARY AMINE-CONTAINING DRUG SUBSTANCES | SEATTLE GENETICS, INC. (US) | 2017-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170247412-A1 | TARGETED DELIVERY OF TERTIARY AMINE-CONTAINING DRUG SUBSTANCES | CD47, CD44, MSR1 | ADRA1A 664/4885PAOX 2341/4885ALDH1A1 913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.