Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18603 | 0.76 | ALDH1A1 (0.43) | ALDH1A1HSD17B10ACHELMNACES1 | |
| SCHEMBL193215 | 0.76 | ALDH1A1 (0.43) | ALDH1A1HSD17B10ACHELMNACES1 | |
| SCHEMBL3885956 | 0.74 | ALDH1A1 (0.52) | ALDH1A1HSD17B10ACHELMNATSHR | |
| SCHEMBL146709 | 0.74 | ALDH1A1 (0.44) | ALDH1A1HSD17B10ACHELMNACES1 | |
| SCHEMBL218653 | 0.74 | HSD17B10 (0.52) | ALDH1A1HSD17B10ACHELMNACES1 | |
| SCHEMBL193032 | 0.74 | HSD17B10 (0.47) | ALDH1A1HSD17B10ACHELMNACES1 | |
| SCHEMBL973063 | 0.74 | ALDH1A1 (0.44) | ALDH1A1HSD17B10ACHECES1TSHR | |
| SCHEMBL8715421 | 0.72 | ALDH1A1 (0.40) | ALDH1A1HSD17B10ACHELMNACES1 | |
| SCHEMBL5671205 | 0.70 | MAPT (0.56) | ALDH1A1HSD17B10ACHELMNATSHR | |
| SCHEMBL3282224 | 0.69 | TDP1 (0.52) | ALDH1A1LMNACES1TSHRCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363632-B1 | RECEPTOR SELECTIVE CANNABIMIMETIC AMINOALKYLINDOLES | UNIV CONNECTICUT (US) | 2010-08-25 | — | — | EP | claimed |
| US-7173027-B2 | Receptor selective cannabimimetic aminoalkylindoles | UNIVERSITY OF CONNECTICUT (US) | 2007-02-06 | — | — | US | claimed |
| JP-2005503998-A | — | — | 2005-02-10 | — | — | JP | claimed |
| EP-1363632-A4 | RECEPTOR SELECTIVE CANNABIMIMETIC AMINOALKYLINDOLES | UNIV CONNECTICUT HEALTH CT (US) | 2004-09-22 | — | — | EP | claimed |
| US-20040077851-A1 | Receptor selective cannabimimetic aminoalkylindoles | CONNECTICUT, UNIVERSITY OF | 2004-04-22 | — | — | US | claimed |
| EP-1363632-A1 | RECEPTOR SELECTIVE CANNABIMIMETIC AMINOALKYLINDOLES | University of Connecticut Health Center (US) | 2003-11-26 | — | — | EP | claimed |
| WO-2002060447-A1 | RECEPTOR SELECTIVE CANNABIMIMETIC AMINOALKYLINDOLES | UNIVERSITY OF CONNECTICUT (US) | 2002-08-08 | — | — | WO | claimed |
| EP-2900645-B1 | HERBICIDAL AND FUNGICIDAL 3-PHENYLISOXAZOLIN DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2019-08-21 | — | — | EP | disclosed |
| US-9585392-B2 | 3-phenylisoxazolin derivatives with herbicidal action | BAYER CROPSCIENCE AG (DE) | 2017-03-07 | — | — | US | disclosed |
| US-20150245615-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | BAYER CROPSCIENCE AG (DE) | 2015-09-03 | — | — | US | disclosed |
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |
| US-7820144-B2 | Receptor selective cannabimimetic aminoalkylindoles | UNIVERSITY OF CONNECTICUT (US) | 2010-10-26 | — | — | US | disclosed |
| WO-2008005908-A2 | PYRIDOIMIDAZOLE DERIVATIVES | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2008-01-10 | — | — | WO | disclosed |
| US-20070243134-A1 | Receptor Selective Cannabimimetic Aminoalkylindoles | CONNECTICUT, UNIVERSITY OF | 2007-10-18 | — | — | US | disclosed |
| US-7241799-B2 | Cannabimimetic indole derivatives | UNIVERSITY OF CONNECTICUT (US) | 2007-07-10 | — | — | US | disclosed |
| US-7173027-B2 | Receptor selective cannabimimetic aminoalkylindoles | UNIVERSITY OF CONNECTICUT (US) | 2007-02-06 | — | — | US | disclosed |
| EP-1702617-A1 | Cannabimimetic indole derivatives | THE UNIVERSITY OF CONNECTICUT (US) | 2006-09-20 | — | — | EP | disclosed |
| US-20050119234-A1 | Cannabimimetic indole derivatives | UNIVERSITY OF CONNECTICUT (US) | 2005-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119234-A1 | Cannabimimetic indole derivatives | CNR2, CNR1, HTR2C | ALDH1A1 3887/4885HSD17B10 2477/4885ACHE 1686/4885 |
| US-20070243134-A1 | Receptor Selective Cannabimimetic Aminoalkylindoles | CNR2, CNR1, GPR18 | ALDH1A1 3295/4885HSD17B10 3466/4885ACHE 540/4885 |
| US-20040077851-A1 | Receptor selective cannabimimetic aminoalkylindoles | CNR2, CNR1, GPR18 | ALDH1A1 3559/4885HSD17B10 3183/4885ACHE 656/4885 |
| US-20150245615-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | CYP4X1, CBR3, PAOX | ALDH1A1 1019/4885HSD17B10 708/4885ACHE 746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.