Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL193215 | 0.77 | ALDH1A1 (0.43) | ALDH1A1HSD17B10ACHELMNACES1 | |
| SCHEMBL6047839 | 0.76 | MEN1 (0.34) | ALDH1A1LMNA | |
| SCHEMBL290002 | 0.76 | ACHE (0.46) | ALDH1A1HSD17B10ACHELMNATSHR | |
| SCHEMBL6047845 | 0.76 | TDP1 (0.32) | ALDH1A1LMNATDP1 | |
| SCHEMBL1921008 | 0.76 | ALDH1A1 (0.46) | ALDH1A1HSD17B10LMNATSHRCA1 | |
| SCHEMBL2441755 | 0.76 | ALDH1A1 (0.36) | ALDH1A1LMNATSHRTDP1MAPT | |
| SCHEMBL2040645 | 0.76 | MAPK1 (0.41) | ALDH1A1HSD17B10LMNATSHRTDP1 | |
| SCHEMBL2684523 | 0.76 | ATM (0.41) | ALDH1A1LMNATSHRTDP1MAPT | |
| SCHEMBL193032 | 0.76 | HSD17B10 (0.47) | ALDH1A1HSD17B10ACHELMNACES1 | |
| SCHEMBL973063 | 0.76 | ALDH1A1 (0.44) | ALDH1A1HSD17B10ACHECES1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1427 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3201208-B1 | BORONIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2021-03-24 | — | — | EP | claimed |
| EP-3201207-B1 | BORONIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2021-02-24 | — | — | EP | claimed |
| EP-3201205-B1 | BORONIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2020-05-13 | — | — | EP | claimed |
| US-10640520-B2 | Boronic acid derivatives | MERCK PATENT GMBH (DE) | 2020-05-05 | — | — | US | claimed |
| CN-108047178-B | A series of new dihydro gibberellin and the preparation method and application thereof | 中国农业大学 | 2019-09-27 | — | — | CN | claimed |
| US-10294246-B2 | Substituted boronic acids and boronate esters as immunoproteasome inhibitors | MERCK PATENT GMBH (DE) | 2019-05-21 | — | — | US | claimed |
| EP-2814831-B1 | NEW QUATERNARY AMMONIUM SALTS, METHOD FOR PREPARATION AND APPLICATIONS THEREOF | UNIV MEDYCZNY IM KAROLA MARCINKOWSKIEGO (PL) | 2018-08-01 | — | — | EP | claimed |
| US-20180179231-A1 | BORONIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2018-06-28 | — | — | US | claimed |
| CN-108047178-A | A series of new dihydro gibberellin and preparation method and application | 中国农业大学 | 2018-05-18 | — | — | CN | claimed |
| US-20180105538-A1 | BORONIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2018-04-19 | — | — | US | claimed |
| CN-1103866-A | Nes pesticides | RHONE POULENC AGRICULTURE (GB) | 1995-06-21 | — | — | CN | claimed |
| EP-0634404-A1 | Phtalazin derivatives and their use as pesticides | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-01-18 | — | — | EP | claimed |
| EP-0422178-B1 | PYRIMIDINE DERIVATIVES | ZENECA LTD (GB) | 1994-10-05 | — | — | EP | claimed |
| US-5332737-A | Cardiovascular disorders | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-07-26 | — | — | US | claimed |
| EP-0453197-B1 | Amine derivatives | ICI PLC (GB) | 1994-06-15 | — | — | EP | claimed |
| CN-1024793-C | Pyrimiding derivatives | ICI PLC (GB) | 1994-06-01 | — | — | CN | claimed |
| US-5223505-A | PYRIMIDINE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-06-29 | — | — | US | claimed |
| EP-0453197-A1 | Amine derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-10-23 | — | — | EP | claimed |
| EP-0431856-A2 | Heterocyclic compounds | ZENECA LIMITED (GB) | 1991-06-12 | — | — | EP | claimed |
| CN-1047080-A | Pyrimidine derivatives | ICI PLC (GB) | 1990-11-21 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180179231-A1 | BORONIC ACID DERIVATIVES | BCL9, BCL9L, BCL6 | ALDH1A1 1217/4885HSD17B10 2801/4885ACHE 4648/4885 |
| US-20180105538-A1 | BORONIC ACID DERIVATIVES | BCL9, BCL9L, BCL6 | ALDH1A1 1217/4885HSD17B10 2801/4885ACHE 4648/4885 |
| US-10640520-B2 | Boronic acid derivatives | BCL9, BCL9L, BCL6 | ALDH1A1 1217/4885HSD17B10 2801/4885ACHE 4648/4885 |
| US-10294246-B2 | Substituted boronic acids and boronate esters as immunoproteasome inhibitors | PSMB7, PSMA7, PSMB11 | ALDH1A1 2896/4885HSD17B10 2729/4885ACHE 4022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.