Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 17/20 | 0.77 |
| ▸ | NR3C1 | P04150 | 15/20 | 0.77 |
| ▸ | NR3C2 | P08235 | 7/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1931030 | 0.90 | PGR (0.74) | PGRNR3C1NR3C2MAPTKDM4E | |
| SCHEMBL291141 | 0.87 | PGR (1.00) | PGRNR3C1NR3C2ALDH1A1 | |
| SCHEMBL4439287 | 0.86 | PGR (0.72) | PGRNR3C1NR3C2ALDH1A1 | |
| SCHEMBL1931135 | 0.86 | PGR (0.74) | PGRNR3C1NR3C2MAPTKDM4E | |
| SCHEMBL1932156 | 0.85 | PGR (0.73) | PGRNR3C1NR3C2MAPTKDM4E | |
| SCHEMBL1932683 | 0.84 | NR3C1 (0.79) | PGRNR3C1NR3C2ALDH1A1MAPT | |
| SCHEMBL1930981 | 0.83 | PGR (0.73) | PGRNR3C1NR3C2MAPTKDM4E | |
| SCHEMBL1931759 | 0.83 | NR3C1 (0.67) | PGRNR3C1NR3C2ALDH1A1MAPT | |
| SCHEMBL1931908 | 0.82 | PGR (0.75) | PGRNR3C1NR3C2MAPTKDM4E | |
| SCHEMBL1932885 | 0.81 | PGR (0.76) | PGRNR3C1NR3C2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110137038-A1 | SYNTHESIS OF SELECTED STEREOISOMERS OF CERTAIN SUBSTITUTED ALCOHOLS | BAUSCH & LOMB INCORPORATED | 2011-06-09 | — | — | US | disclosed |
| US-20080114172-A1 | Synthesis of Selected Stereoisomers of Certain Substituted Alcohols | BAUSCH & LOMB INCORPORATED | 2008-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080114172-A1 | Synthesis of Selected Stereoisomers of Certain Substituted Alcohols | ADH1A, ADH1C, CYP2E1 | PGR 2372/4885NR3C1 203/4885NR3C2 116/4885 |
| US-20110137038-A1 | SYNTHESIS OF SELECTED STEREOISOMERS OF CERTAIN SUBSTITUTED ALCOHOLS | ADH1A, ADH1C, CYP2E1 | PGR 2372/4885NR3C1 203/4885NR3C2 116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.