Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19308224 | 0.85 | F2 (0.49) | ALDH1A1HTTPKMKMT2AMEN1 | |
| SCHEMBL8546806 | 0.83 | AKR1C3 (0.51) | ALDH1A1HTTPKMKMT2AMEN1 | |
| SCHEMBL12929490 | 0.78 | ALDH1A1 (0.57) | ALDH1A1HTTPKMKMT2AMEN1 | |
| SCHEMBL5275182 | 0.77 | TSHR (0.59) | ALDH1A1PKMKMT2AMEN1GAA | |
| SCHEMBL6793156 | 0.76 | GPR119 (0.50) | ALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL19308198 | 0.76 | TSHR (0.47) | ALDH1A1GAALMNAF10F2 | |
| SCHEMBL19308209 | 0.75 | ALDH1A1 (0.57) | ALDH1A1HTTKMT2AMEN1GAA | |
| SCHEMBL12929486 | 0.75 | ALDH1A1 (0.53) | ALDH1A1HTTPKMKMT2AMEN1 | |
| SCHEMBL19308229 | 0.75 | F2 (0.52) | ALDH1A1HTTPKMKMT2AGAA | |
| SCHEMBL19308208 | 0.72 | HDAC3 (0.47) | ALDH1A1LMNAF10F2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9752149-B2 | Matriptase inhibitors and uses thereof against orthomyxoviridae infections | SOCPRA Sciences Sante et Humaines S.E.C. (CA) | 2017-09-05 | — | — | US | disclosed |