Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 9/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 8/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 3/20 | 0.44 |
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.44 |
| ▸ | PLAU | P00749 | 2/20 | 0.44 |
| ▸ | PROC | P04070 | 1/20 | 0.43 |
| ▸ | HPN | P05981 | 1/20 | 0.43 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19308204 | 0.85 | ALDH1A1 (0.51) | F2ALDH1A1HTTPKMMEN1 | |
| SCHEMBL8546806 | 0.80 | AKR1C3 (0.51) | ALDH1A1HTTPKMMEN1RAB9A | |
| SCHEMBL12929574 | 0.80 | ALDH1A1 (0.54) | F2ALDH1A1HTTPKMMEN1 | |
| SCHEMBL19308229 | 0.79 | F2 (0.52) | F2ALDH1A1HTTPKMKMT2A | |
| SCHEMBL19308220 | 0.77 | F2 (0.44) | F2ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL19308197 | 0.75 | HDAC3 (0.46) | F2ALDH1A1HTTF10LMNA | |
| SCHEMBL5275182 | 0.74 | TSHR (0.59) | F2ALDH1A1PKMMEN1KMT2A | |
| SCHEMBL6793156 | 0.74 | GPR119 (0.50) | ALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL19308200 | 0.73 | F2 (0.43) | F2F10PRSS1LMNAPLG | |
| SCHEMBL19308228 | 0.73 | MC4R (0.47) | F2ALDH1A1HTTPKMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9752149-B2 | Matriptase inhibitors and uses thereof against orthomyxoviridae infections | SOCPRA Sciences Sante et Humaines S.E.C. (CA) | 2017-09-05 | — | — | US | disclosed |