Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.47 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | FABP2 | P12104 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19400432 | 0.94 | TAAR1 (0.55) | TAAR1ESR2PDK2PDE3BPDE3A | |
| SCHEMBL12384873 | 0.92 | TAAR1 (0.55) | TAAR1ESR2PDK2PDE3BPDE3A | |
| SCHEMBL19400433 | 0.89 | MEN1 (0.50) | PDE3BPDE3AALOX5APFEN1PTGS1 | |
| SCHEMBL2140807 | 0.87 | PTGS1 (0.49) | PDE3BPDE3AALOX5APFEN1CYP11B2 | |
| SCHEMBL28566500 | 0.87 | PTGS1 (0.49) | PDE3BPDE3AALOX5APFEN1CYP11B2 | |
| SCHEMBL15077185 | 0.87 | PTGS1 (0.49) | PDE3BPDE3AALOX5APFEN1CYP11B2 | |
| SCHEMBL21363824 | 0.87 | TAAR1 (0.47) | TAAR1ESR2PDK2PDE3BPDE3A | |
| SCHEMBL14479222 | 0.86 | PTPRC (0.53) | TAAR1ESR2PDK2PDE3BPDE3A | |
| SCHEMBL19288225 | 0.86 | TAAR1 (0.55) | TAAR1ESR2PDK2PDE3BPDE3A | |
| SCHEMBL18716177 | 0.86 | CYP2C9 (0.47) | PDK2PDE3BPDE3AALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240072425-A1 | AROMATIC ISOTHIOCYANATES | MERCK PATENT GMBH (DE) | 2024-02-29 | — | — | US | disclosed |
| US-11834599-B2 | Aromatic isothiocyanates | MERCK PATENT GMBH (DE) | 2023-12-05 | — | — | US | disclosed |
| US-11739265-B2 | Aromatic isothiocyanates | MERCK PATENT GMBH (DE) | 2023-08-29 | — | — | US | disclosed |
| EP-3739020-B1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2023-08-23 | — | — | EP | disclosed |
| US-11667840-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2023-06-06 | — | — | US | disclosed |
| US-20230025385-A1 | FLUORINATED AROMATIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2023-01-26 | — | — | US | disclosed |
| WO-2022090099-A1 | AROMATIC ISOTHIOCYANATES | MERCK PATENT GMBH (DE) | 2022-05-05 | — | — | WO | disclosed |
| US-11306251-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2022-04-19 | — | — | US | disclosed |
| US-11268026-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2022-03-08 | — | — | US | disclosed |
| EP-3433236-B1 | CYANOPYRIMIDINE DERIVATIVES SUITABLE AS COMPONENTS IN LIQUID CRYSTAL MEDIA | MERCK PATENT GMBH (DE) | 2021-10-27 | — | — | EP | disclosed |
| US-20190185747-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2019-06-20 | — | — | US | disclosed |
| EP-2753676-B1 | LIQUID-CRYSTALLINE MEDIUM AND HIGH-FREQUENCY COMPONENTS COMPRISING SAME | MERCK PATENT GMBH (DE) | 2019-01-23 | — | — | EP | disclosed |
| WO-2018077765-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2018-05-03 | — | — | WO | disclosed |
| US-9938462-B2 | Liquid-crystalline media, components for high-frequency technology, and mesogenic compounds | MERCK PATENT GMBH (DE) | 2018-04-10 | — | — | US | disclosed |
| EP-2935513-B1 | LIQUID-CRYSTALLINE MEDIA, COMPONENTS FOR HIGH-FREQUENCY TECHNOLOGY, AND MESOGENIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2018-03-07 | — | — | EP | disclosed |
| WO-2018036985-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2018-03-01 | — | — | WO | disclosed |
| US-9790426-B2 | Components for high-frequency technology, and liquid-crystalline media | MERCK PATENT GMBH (DE) | 2017-10-17 | — | — | US | disclosed |
| WO-2017162707-A1 | CYANOPYRIMIDINE DERIVATIVES SUITABLE AS COMPONENTS IN LIQUID CRYSTAL MEDIA | MERCK PATENT GMBH (DE) | 2017-09-28 | — | — | WO | disclosed |
| US-9765259-B2 | Mesogenic compounds, liquid-crystalline media and components for high-frequency technology | MERCK PATENT GMBH (DE) | 2017-09-19 | — | — | US | disclosed |
| US-9752077-B2 | Liquid-crystalline media, components for high-frequency technology, and mesogenic compounds | MERCK PATENT GMBH (DE) | 2017-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240072425-A1 | AROMATIC ISOTHIOCYANATES | TRPA1, TRPC1, CRY1 | TAAR1 101/4885ESR2 3395/4885PDK2 4357/4885 |
| US-20230025385-A1 | FLUORINATED AROMATIC COMPOUNDS | TRPA1, FOXM1, AFF1 | TAAR1 40/4885ESR2 3581/4885PDK2 4366/4885 |
| US-11667840-B2 | Liquid-crystalline medium | FES, BLM, CXCL12 | TAAR1 271/4885ESR2 3456/4885PDK2 1419/4885 |
| US-20190185747-A1 | LIQUID-CRYSTALLINE MEDIUM | CCNI, CCNT2, C1QBP | TAAR1 1021/4885ESR2 4660/4885PDK2 4288/4885 |
| US-11739265-B2 | Aromatic isothiocyanates | TRPA1, CRY1, FOXM1 | TAAR1 68/4885ESR2 2846/4885PDK2 4419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.