Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.71 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.53 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.52 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.52 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.52 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29425720 | 1.00 | CES2 (0.71) | CES2SRD5A2LMNANPSR1P2RX1 | |
| Ethane SCHEMBL27364386 | 0.96 | CES2 (0.67) | CES2SRD5A2LMNANPSR1P2RX1 | |
| SCHEMBL7729073 | 0.90 | KCNK3 (0.63) | CES2SRD5A2LMNANPSR1P2RX1 | |
| SCHEMBL5349991 | 0.85 | CES2 (0.52) | CES2SRD5A2LMNANPSR1P2RX1 | |
| SCHEMBL11725067 | 0.85 | CES2 (0.79) | CES2SRD5A2LMNANPSR1P2RX1 | |
| SCHEMBL8775382 | 0.85 | CES2 (0.52) | CES2SRD5A2LMNANPSR1P2RX1 | |
| SCHEMBL2012089 | 0.84 | MAPT (0.76) | LMNAP2RX1POLBMAPTMEN1 | |
| SCHEMBL1019311 | 0.84 | CES2 (0.53) | CES2SRD5A2LMNANPSR1P2RX1 | |
| SCHEMBL3176325 | 0.83 | CES2 (1.00) | CES2SRD5A2LMNANPSR1P2RX1 | |
| SCHEMBL1237189 | 0.83 | SRD5A2 (0.79) | CES2SRD5A2LMNANPSR1P2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2665 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120020114-A | Preparation method of N-alkenyl amide compound | 中国石油化工股份有限公司 | 2025-05-20 | — | — | CN | claimed |
| CN-120020115-A | Process for the preparation of N- (alkyl-2-hydroxy) alkylamides and N-alkenylamides | 中国石油化工股份有限公司 | 2025-05-20 | — | — | CN | claimed |
| CN-117384167-A | Dihydropyrimidine [4,5-d ] pyrimidine-2 (H) -ketone Nrf2 activator and preparation method and application thereof | 寒武智元(南京)生物医药科技有限公司 | 2024-01-12 | — | — | CN | claimed |
| CN-117343077-A | Isoindolinone morpholine derivative and preparation method and application thereof | 南开大学 | 2024-01-05 | — | — | CN | claimed |
| CN-114736354-B | Preparation method and application of resveratrol-based all-bio-based epoxy resin | 中科院广州化学有限公司 | 2023-09-12 | — | — | CN | claimed |
| CN-114195772-B | 1,2, 4-oxadiazole derivative containing 1,3, 4-thiadiazole unit, and preparation method and application thereof | 贵州大学 | 2023-06-30 | — | — | CN | claimed |
| CN-115399179-A | Application of polysaccharide-based cationic polymer in prevention and treatment of soil-borne diseases of agriculture and forestry | 中国科学院化学研究所 | 2022-11-29 | — | — | CN | claimed |
| CN-114736354-A | Preparation method and application of resveratrol-based all-bio-based epoxy resin | 中科院广州化学有限公司 | 2022-07-12 | — | — | CN | claimed |
| CN-111662275-A | Benzenesulfonamide IDH mutant inhibitor, preparation method and application thereof | 中国药科大学 | 2020-09-15 | — | — | CN | claimed |
| US-20190350903-A1 | INDOMETHACIN ANALOGS FOR THE TREATMENT OF CASTRATE-RESISTANT PROSTATE CANCER | VANDERBILT UNIVERSITY (US) | 2019-11-21 | — | — | US | claimed |
| EP-0666260-B1 | 3-(2-aminoethyl)-4-3-(trifluoromethyl)benzoyl-3,4-dihydro-2H-1,4-benzoxazine derivatives, their preparation and use in therapy | SYNTHELABO (FR) | 1999-08-04 | — | — | EP | claimed |
| EP-0639559-B1 | Preparation of 1,2-diacyl-2-(t-alkyl)hydrazines | ROHM & HAAS (US) | 1997-10-15 | — | — | EP | claimed |
| CN-1109880-A | 3-(2-aminoethyl)-4-[3-(trifluoromethyl) benzoyl]-3,4-dihydro-1,4-benzoxazine derivative and preparation of same | SYNTHELABO (FR) | 1995-10-11 | — | — | CN | claimed |
| EP-0639559-A1 | Preparation of 1,2-diacyl-2-(t-alkyl)hydrazines | ROHM AND HAAS COMPANY (US) | 1995-02-22 | — | — | EP | claimed |
| WO-1993014055-A1 | PREPARATION OF 2,5-DICHLOROBENZOPHENONES | MAXDEM INCORPORATED (US) | 1993-07-22 | — | — | WO | claimed |
| US-5210313-A | Friedel crafts aryloylation of 1,4-dichlorobenzene and Lewis acids | MAXDEM INCORPORATED (US) | 1993-05-11 | — | — | US | claimed |
| US-4581179-A | Process for the preparation of trifluoromethylbenzoyl chlorides and bromides from trifluoromethylbenzoyl fluorides | OCCIDENTAL CHEMICAL CORPORATION (US) | 1986-04-08 | — | — | US | claimed |
| US-4500471-A | REACTING TRICHLORO-OR TRIBROMOMETHYLBENZOYL HALIDES WITH HYDROGEN FLORIDE | OCCIDENTAL CHEMICAL CORPORATION (US) | 1985-02-19 | — | — | US | claimed |
| EP-0038223-B1 | PROCESS FOR THE PREPARATION OF TRIFLUOROMETHYLBENZOYL HALIDES | OCCIDENTAL CHEMICAL CORPORATION (US) | 1984-08-08 | — | — | EP | claimed |
| EP-0038223-A1 | Process for the preparation of trifluoromethylbenzoyl halides | OCCIDENTAL CHEMICAL CORPORATION (US) | 1981-10-21 | — | — | EP | claimed |