SCHEMBL29425720

SCHEMBL29425720

O=C(Cl)c1cccc(C(F)(F)F)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.71
SRD5A2 P31213 1/20 0.59
LMNA P02545 2/20 0.56
NPSR1 Q6W5P4 1/20 0.56
P2RX1 P51575 1/20 0.56
POLB P06746 2/20 0.54
HPGD P15428 1/20 0.54
MAPT P10636 1/20 0.53
ALDH1A1 P00352 2/20 0.53
MAOB P27338 1/20 0.53
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
KCNK3 O14649 1/20 0.53
KCNQ3 O43525 1/20 0.52
KCNQ2 O43526 1/20 0.52
KCNE1 P15382 1/20 0.52
KCNQ1 P51787 1/20 0.52
PTGS1 P23219 1/20 0.51
CNR1 P21554 1/20 0.51
TLR7 Q9NYK1 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19310 1.00 CES2 (0.71) CES2SRD5A2LMNANPSR1P2RX1
Ethane SCHEMBL27364386 0.96 CES2 (0.67) CES2SRD5A2LMNANPSR1P2RX1
SCHEMBL7729073 0.90 KCNK3 (0.63) CES2SRD5A2LMNANPSR1P2RX1
SCHEMBL5349991 0.85 CES2 (0.52) CES2SRD5A2LMNANPSR1P2RX1
SCHEMBL11725067 0.85 CES2 (0.79) CES2SRD5A2LMNANPSR1P2RX1
SCHEMBL8775382 0.85 CES2 (0.52) CES2SRD5A2LMNANPSR1P2RX1
SCHEMBL2012089 0.84 MAPT (0.76) LMNAP2RX1POLBMAPTMEN1
SCHEMBL1019311 0.84 CES2 (0.53) CES2SRD5A2LMNANPSR1P2RX1
SCHEMBL3176325 0.83 CES2 (1.00) CES2SRD5A2LMNANPSR1P2RX1
SCHEMBL1237189 0.83 SRD5A2 (0.79) CES2SRD5A2LMNANPSR1P2RX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122071464-A Heterocyclic compound, pharmaceutical composition thereof and application thereof 上海璎黎药业有限公司 2026-05-22 CN disclosed
CN-122029155-A Heterocyclic compound and harmful arthropod control composition containing same 住友化学株式会社 2026-05-12 CN disclosed
CN-120699015-B Pyridopyrimidine compound containing morpholine structure, and preparation method and application thereof 江西科技师范大学 2026-05-12 CN disclosed
WO-2025096956-A1 DCN-1 MODULATING COMPOUNDS AND METHODS OF USE THEREOF CELLARITY, INC. (US) 2025-05-08 WO disclosed
CN-115279747-B FYN and VEGFR2 kinase inhibitors 罗达制药生物技术有限责任公司 2024-11-05 CN disclosed
CN-115466223-B Heterocyclic benzamide compound and application thereof in promoting plant growth and development 南方科技大学 2024-07-19 CN disclosed
EP-4380939-A1 COMPOUNDS CONSTITUTING C20-MODIFIED SALINOMYCIN DERIVATIVES, A METHOD FOR OBTAINING THE SAME, A COMPOSITION CONTAINING THE SAME AND A USE OF SAID COMPOUNDS Fileclo Spolka Z Ograniczona Odpowiedzialnoscia (PL) 2024-06-12 EP disclosed
CN-114901646-B Benzotriazine bisoxides and pharmaceutical compositions thereof 浙江瑞臻医药有限公司 2024-06-04 CN disclosed
CN-117836306-A Galactose glycoside derivatives as galectin-3 inhibitors 株式会社蒂奥姆生物 2024-04-05 CN disclosed
CN-117836299-A Novel bifunctional heterocyclic compounds with Bruton tyrosine kinase decomposition via ubiquitin proteasome pathway and uses thereof 韩国化学研究院 2024-04-05 CN disclosed
CN-115141197-A 3-aromatic heterocyclic substituted phenyl derivative and preparation method and application thereof 安徽医科大学 2022-10-04 CN disclosed
CN-114901646-A Benzotriazine double oxide and pharmaceutical composition thereof 杭州瑞臻医药有限公司 2022-08-12 CN disclosed
EP-4037685-A1 QUINOLINES THAT MODULATE SERCA AND THEIR USE FOR TREATING DISEASE Neurodon Corporation (US) 2022-08-10 EP disclosed
CN-114644583-A Indole derivative and preparation method and application thereof 中国医学科学院医药生物技术研究所 2022-06-21 CN disclosed
CN-108794411-B Certain chemical entities, compositions, and methods 润新生物公司 2022-06-07 CN disclosed
CN-113243374-B Heterocyclic compounds as pesticides 拜耳农作物科学股份公司 2022-04-26 CN disclosed
CN-114181199-A 2, 4-disubstituted pyrimidine derivative and preparation method and application thereof 成都赜灵生物医药科技有限公司 2022-03-15 CN disclosed
WO-2022046861-A1 MODULATORS OF MYC FAMILY PROTO-ONCOGENE PROTEIN NALO THERAPEUTICS (US) 2022-03-03 WO disclosed
WO-2022045231-A1 ESTER COMPOUND 三井化学株式会社 2022-03-03 WO disclosed
WO-2022032071-A1 KINASE INHIBITORS AND USES THEREOF ABM THERAPEUTICS CORPORATION (US) 2022-02-10 WO disclosed