Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 3/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.40 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5349991 | 0.85 | CES2 (0.52) | CES2ACHESRD5A2ALDH1A1TSHR | |
| SCHEMBL19310 | 0.85 | CES2 (0.71) | CES2SRD5A2ALDH1A1LMNANPSR1 | |
| SCHEMBL29425720 | 0.85 | CES2 (0.71) | CES2SRD5A2ALDH1A1LMNANPSR1 | |
| SCHEMBL29420736 | 0.83 | SRD5A2 (0.57) | CES2ACHESRD5A2LMNAHPGD | |
| SCHEMBL545227 | 0.83 | SRD5A2 (0.57) | CES2ACHESRD5A2LMNAHPGD | |
| Ethane SCHEMBL27364386 | 0.81 | CES2 (0.67) | CES2SRD5A2ALDH1A1LMNANPSR1 | |
| SCHEMBL30144846 | 0.80 | CES2 (0.50) | CES2ACHESRD5A2ALDH1A1TSHR | |
| SCHEMBL4861345 | 0.79 | TSHR (0.47) | CES2ACHESRD5A2ALDH1A1TSHR | |
| SCHEMBL1360237 | 0.77 | ACHE (0.62) | CES2ACHEALDH1A1TSHRNPSR1 | |
| SCHEMBL29540544 | 0.77 | ACHE (0.62) | CES2ACHEALDH1A1TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641831-B1 | Organopolysiloxane-grafted polybenzobisoxazoles and method for preparing same | DOW CORNING ASIA LTD (JP) | 1997-11-12 | — | — | EP | disclosed |
| EP-0641831-A1 | Organopolysiloxane-grafted polybenzobisoxazoles and method for preparing same | DOW CORNING ASIA, Ltd. (JP) | 1995-03-08 | — | — | EP | disclosed |
| EP-0361416-A1 | Polyamides prepared from 2-(3-aminophenyl)-2-(4-aminophenyl) hexafluoro propane | HOECHST CELANESE CORPORATION (US) | 1990-04-04 | — | — | EP | disclosed |
| US-4914180-A | Polyamides prepared from 2-(3-aminophenyl)-2-(4-aminophenyl) hexafluoro propane | HOECHST CELANESE CORPORATION (US) | 1990-04-03 | — | — | US | disclosed |