SCHEMBL1931206

SCHEMBL1931206

COC(=O)C(C)Oc1ccc(OC(=O)CO)cc1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.47
MAPT P10636 4/20 0.47
ALDH1A1 P00352 4/20 0.47
LMNA P02545 2/20 0.47
HSD17B10 Q99714 2/20 0.47
HTT P42858 1/20 0.47
MEN1 O00255 4/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
ALDH2 P05091 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.43
POLB P06746 1/20 0.43
TAS1R3 Q7RTX0 1/20 0.42
TAS1R1 Q7RTX1 1/20 0.42
TAS1R2 Q8TE23 1/20 0.42
KLK7 P49862 2/20 0.42
KDM4E B2RXH2 2/20 0.40
HPGD P15428 1/20 0.40
TSHR P16473 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4250581 0.84 KMT2A (0.58) KMT2AMAPTALDH1A1LMNAHSD17B10
SCHEMBL9839367 0.81 MAPT (0.50) KMT2AMAPTALDH1A1LMNAHSD17B10
SCHEMBL4268398 0.81 CYP4F2 (0.51) KMT2AMAPTALDH1A1LMNAMEN1
SCHEMBL7220225 0.80 KMT2A (0.49) KMT2AMAPTALDH1A1LMNAHSD17B10
SCHEMBL16728392 0.79 TAS1R3 (0.65) KMT2AMAPTALDH1A1LMNAMEN1
SCHEMBL11402555 0.79 TAS1R3 (0.65) KMT2AMAPTALDH1A1LMNAMEN1
SCHEMBL9063033 0.79 CYP1A2 (0.59) KMT2AMAPTALDH1A1HSD17B10MEN1
SCHEMBL832097 0.78 KMT2A (0.52) KMT2AMAPTALDH1A1LMNAHTT
SCHEMBL8431462 0.78 KMT2A (0.52) KMT2AMAPTALDH1A1LMNAHSD17B10
SCHEMBL14122122 0.78 KMT2A (0.66) KMT2AMAPTALDH1A1LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8372882-B2 Functionalized phenolic esters and amides and polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2013-02-12 US disclosed
US-8372882-B2 Functionalized phenolic esters and amides and polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2013-02-12 US disclosed
US-8372882-B2 Functionalized phenolic esters and amides and polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2013-02-12 US disclosed
US-20110130448-A1 FUNCTIONALIZED PHENOLIC ESTERS AND AMIDES AND POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2011-06-02 US disclosed
US-20110130448-A1 FUNCTIONALIZED PHENOLIC ESTERS AND AMIDES AND POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2011-06-02 US disclosed
US-20110130448-A1 FUNCTIONALIZED PHENOLIC ESTERS AND AMIDES AND POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2011-06-02 US disclosed
US-7858077-B2 Functionalized phenolic esters and amides and polymers therefrom BEZWADA BIOMEDICAL LLC (US) 2010-12-28 US disclosed
US-7858077-B2 Functionalized phenolic esters and amides and polymers therefrom BEZWADA BIOMEDICAL LLC (US) 2010-12-28 US disclosed
US-7858077-B2 Functionalized phenolic esters and amides and polymers therefrom BEZWADA BIOMEDICAL LLC (US) 2010-12-28 US disclosed
US-20060173065-A1 Functionalized phenolic esters and amides and polymers therefrom BEZWADA BIOMEDICAL LLC 2006-08-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060173065-A1 Functionalized phenolic esters and amides and polymers therefrom HAAO, HAO2, HCAR3 KMT2A 2066/4885MAPT 3480/4885ALDH1A1 132/4885
US-20110130448-A1 FUNCTIONALIZED PHENOLIC ESTERS AND AMIDES AND POLYMERS THEREFROM HAO2, HCAR2, HAAO KMT2A 1798/4885MAPT 3453/4885ALDH1A1 137/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.