Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19313525 | 0.83 | MCHR1 (0.31) | — | |
| SCHEMBL12017385 | 0.80 | CCR1 (0.39) | — | |
| SCHEMBL1818218 | 0.79 | GBA1 (0.41) | — | |
| SCHEMBL27697912 | 0.78 | GABRG2 (0.32) | — | |
| SCHEMBL14840548 | 0.77 | PPARG (0.38) | — | |
| SCHEMBL19313507 | 0.74 | L3MBTL1 (0.34) | — | |
| SCHEMBL15833799 | 0.73 | PIK3CD (0.40) | APP | |
| SCHEMBL2013765 | 0.71 | — | — | |
| SCHEMBL27874773 | 0.71 | — | — | |
| SCHEMBL19222038 | 0.70 | FDPS (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2493889-B1 | IMIDAZO[1,2-b]PYRIDAZINE DERIVATIVES AND THEIR USE AS PDE10 INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2017-09-06 | — | — | EP | disclosed |