Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25006433 | 0.83 | NQO2 (0.38) | — | |
| SCHEMBL25008403 | 0.69 | F2R (0.33) | — | |
| SCHEMBL25008044 | 0.68 | CA1 (0.34) | — | |
| SCHEMBL25006755 | 0.65 | KCNH2 (0.35) | — | |
| SCHEMBL25008019 | 0.63 | PNMT (0.37) | NPC1RAB9A | |
| SCHEMBL27892537 | 0.62 | THRA (0.56) | RARB | |
| SCHEMBL11414654 | 0.61 | ESR1 (0.46) | RAB9A | |
| SCHEMBL9242259 | 0.59 | CA1 (0.41) | — | |
| SCHEMBL9242261 | 0.59 | CA1 (0.41) | — | |
| SCHEMBL25007269 | 0.58 | CA1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968302-B9 | COMBINATION OF DIRECT ACTING ANTIVIRAL AGENTS AND RIBAVIRIN FOR TREATING HCV PATIENTS | ABBVIE INC (US) | 2019-02-13 | — | — | EP | disclosed |
| EP-2968302-B1 | COMBINATION OF DIRECT ACTING ANTIVIRAL AGENTS AND RIBAVIRIN FOR TREATING HCV PATIENTS | ABBVIE INC (US) | 2017-09-06 | — | — | EP | disclosed |