Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25006755 | 0.87 | KCNH2 (0.35) | — | |
| SCHEMBL25006442 | 0.71 | PTGIR (0.37) | PNMTTAAR1HTR3EHTR3BHTR3A | |
| SCHEMBL6570948 | 0.71 | HTR3E (0.49) | PNMTTAAR1TSHRRECQLNPC1 | |
| SCHEMBL197297 | 0.69 | TAAR1 (0.59) | PNMTTAAR1AOC3HTR3EHTR3B | |
| SCHEMBL25008063 | 0.68 | MMP2 (0.39) | OPRM1OPRD1OPRK1 | |
| SCHEMBL6097422 | 0.67 | TAAR1 (0.57) | PNMTTAAR1KMT2AAOC3HTR3E | |
| SCHEMBL14047464 | 0.67 | TAAR1 (0.57) | PNMTTAAR1AOC3HTR3EHTR3B | |
| SCHEMBL25007227 | 0.67 | PTGIR (0.36) | — | |
| SCHEMBL24244205 | 0.66 | LPL (0.57) | TAAR1AOC3HTR3EHTR3BHTR3A | |
| SCHEMBL5599185 | 0.66 | LPL (0.57) | TAAR1AOC3HTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4129402-A1 | HYDROXYPYRROLIDINE DERIVATIVE AND MEDICINAL APPLICATION THEREOF | Mitsubishi Tanabe Pharma Corporation (JP) | 2023-02-08 | — | — | EP | disclosed |